HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	37827155, 35709258
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 1584
+	Hs
		651208 RFA1_HUMAN (1-616): 0: 781: 100.00		MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03
+	Hs
		650614 RFA1_HUMAN (1-616): 0: 781: 100.00		MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56
+	Hs
		652624 RFA1_HUMAN (1-616): 0: 781: 100.00		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		652037 RFA1_HUMAN (1-616): 0: 781: 100.00		MINT_HUMAN (173-1570): 1.59e-17: 91.8: 7.72
+	Hs
		651461 RFA1_HUMAN (1-616): 0: 781: 100.00		NIPBL_HUMAN (588-1406): 4.52e-15: 83.7: 12.73
+	Hs
		651725 RFA1_HUMAN (1-616): 0: 781: 100.00		KMT2C_HUMAN (378-1460): 4.45e-12: 73.7: 11.24
+	Hs
		152593 RFA1_HUMAN (1-616): 0: 781: 100.00		KMT2D_HUMAN (119-1312): 8.58e-09: 62.9: 5.85
+	Dm
		1097979 RFA1_DROME (1-614): 0: 619: 41.00		Q9VLS7_DROME (601-1577): 6.1e-21: 102: 7.84
+	Hs
		1056865 RADX_HUMAN (27-384): 6.8e-66: 233: 16.24		MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03