Interactor 1: IDH2 (P28241)
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH)
Gene: IDH2
Interactor 2: IDH1 (P28834)
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH)
Gene: IDH1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.980 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11283351, 11042198, 32051233, 16554755, 16884682, 18313953, 19645416, 19750512, 37968396, 21133413, 21861471, 19343713, 16429126 |
| Identification Methods | two hybrid pooling approach, two hybrid, cross-linking study, affinity chromatography technology, biochemical, protein complementation assay, x-ray crystallography, pull down, blue native page, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Iso_dh~Iso_dh |
| Common GO terms | GO:0000287 - magnesium ion binding GO:0003723 - RNA binding GO:0004449 - isocitrate dehydrogenase (NAD+) activity GO:0005739 - mitochondrion GO:0006099 - tricarboxylic acid cycle and 3 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
