HitPredict

Interactor 1: SMCA1 (P28370)
Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1)
Gene: SMARCA1

Interactor 2: ARI1B (Q8NFD5)
AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R)
Gene: ARID1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21118156
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0031491 - nucleosome binding GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1054 Hs			1 2319
+	Hs
		847021 SMCA4_HUMAN (60-913): 0: 686: 31.42		ARI1B_HUMAN (21-2319): 0: 845: 100.00
+	Hs
		658687 SMCA1_HUMAN (1-1054): 0: 1130: 100.00		ARI4B_HUMAN (1141-1230): 6.03e-24: 113: 29.03
+	Hs
		1018732 CHD3_HUMAN (31-954): 0: 791: 28.94		KDM5B_HUMAN (1099-1343): 5.47e-29: 129: 16.60
+	Hs
		1117674 CHD5_HUMAN (31-961): 0: 800: 28.13		ARI4B_HUMAN (1141-1230): 6.03e-24: 113: 29.03
+	Hs
		1018515 CHD3_HUMAN (31-954): 0: 791: 28.94		ARI4B_HUMAN (1141-1230): 6.03e-24: 113: 29.03
+	Dm
		332869 CHDM_DROME (27-954): 0: 737: 29.21		KDM5_DROME (943-1317): 8.03e-37: 155: 18.28
+	Mm
		57179 CHD7_MOUSE (3-1046): 0: 788: 26.74		ARI1A_MOUSE (33-1422): 3.42e-18: 94.6: 8.98
+	Hs
		146206 CHD3_HUMAN (31-954): 0: 791: 28.94		ARI1A_HUMAN (718-1922): 1.42e-12: 76.1: 9.49
+	Hs
		146222 CHD4_HUMAN (29-960): 0: 789: 28.27		ARI1A_HUMAN (718-1922): 1.42e-12: 76.1: 9.49
+	Hs
		146292 CHD7_HUMAN (3-1046): 0: 780: 26.74		ARI1A_HUMAN (718-1922): 1.42e-12: 76.1: 9.49
+	Hs
		782323 SMCA4_HUMAN (60-913): 0: 686: 31.42		KDM5C_HUMAN (1099-1341): 1.93e-40: 167: 19.76
+	Hs
		146283 CHD8_HUMAN (2-1011): 0: 769: 27.72		ARI1A_HUMAN (718-1922): 1.42e-12: 76.1: 9.49
+	Hs
		1147487 CHD7_HUMAN (3-1046): 0: 780: 26.74		ARID2_HUMAN (681-1670): 2.53e-09: 65: 13.19
+	Hs
		1336298 CHD8_HUMAN (2-1011): 0: 769: 27.72		CHD7_HUMAN (1174-1670): 1.92e-11: 72.1: 9.96
+	Hs
		867130 CHD8_HUMAN (2-1011): 0: 769: 27.72		SC24C_HUMAN (1301-1654): 3.58e-10: 67.7: 16.07
+	Hs
		146185 SMCA4_HUMAN (60-913): 0: 686: 31.42		ARI1A_HUMAN (718-1922): 1.42e-12: 76.1: 9.49
+	Hs
		847103 SMCA4_HUMAN (60-913): 0: 686: 31.42		CHD7_HUMAN (1174-1670): 1.92e-11: 72.1: 9.96
+	Mm
		57767 SMCA4_MOUSE (60-836): 0: 663: 35.23		ARI1A_MOUSE (33-1422): 3.42e-18: 94.6: 8.98
+	Hs
		846995 SMCA4_HUMAN (60-913): 0: 686: 31.42		ARID2_HUMAN (681-1670): 2.53e-09: 65: 13.19
+	Mm
		57185 SMCA4_MOUSE (60-836): 0: 663: 35.23		CHD7_MOUSE (1003-1582): 2.93e-09: 65.2: 8.62