Interactor 1: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1
Interactor 2: TWF1 (Q12792)
Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9)
Gene: TWF1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35271311 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cofilin_ADF~Cofilin_ADF |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005911 - cell-cell junction GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton and 4 others more... |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025