HitPredict

Interactor 1: KDM5A (P29375)
Lysine-specific demethylase 5A (EC 1.14.11.67) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2) ([histone H3]-trimethyl-L-lysine(4) demethylase 5A)
Gene: KDM5A

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17320161
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1690 Hs			1 136
+	Hs
		666522 KDM5A_HUMAN (1-1690): 0: 1849: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		666535 KDM5A_HUMAN (1-1690): 0: 1849: 100.00		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		666523 KDM5A_HUMAN (1-1690): 0: 1849: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		1086304 KDM5D_HUMAN (8-1602): 0: 1482: 47.25		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Dm
		356114 KDM5_DROME (13-1668): 0: 1479: 39.47		H3_DROME (1-136): 3.73e-61: 186: 100.00
+	Hs
		782353 KDM5C_HUMAN (8-1593): 0: 1427: 48.81		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Sp
		457185 LID2_SCHPO (30-1368): 0: 877: 20.10		H31_SCHPO (1-136): 2.22e-59: 181: 91.91
+	Sp
		498409 LID2_SCHPO (30-1368): 0: 877: 20.10		H33_SCHPO (1-136): 4.37e-58: 177: 91.18
+	Sc
		902025 ECM5_YEAST (14-1309): 0: 759: 15.76		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Sc
		812506 JHD2_YEAST (16-705): 3.56e-155: 494: 26.09		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Hs
		183098 KDM6A_HUMAN (329-736): 6.2e-89: 321: 17.82		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		183122 KDM6A_HUMAN (329-736): 6.2e-89: 321: 17.82		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		183127 KDM6A_HUMAN (329-736): 6.2e-89: 321: 17.82		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		935339 KDM5B_HUMAN (856-1664): 3.65e-85: 311: 19.17		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		301134 KDM4B_HUMAN (330-663): 7.98e-85: 305: 24.79		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		301136 KDM4B_HUMAN (330-663): 7.98e-85: 305: 24.79		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		301146 KDM4B_HUMAN (330-663): 7.98e-85: 305: 24.79		H3C_HUMAN (1-136): 8.83e-59: 179: 94.12
+	Hs
		935232 KDM4C_HUMAN (330-655): 7.67e-82: 295: 24.50		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1174653 KDM4C_HUMAN (330-655): 7.67e-82: 295: 24.50		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		952622 KDM4C_HUMAN (330-655): 7.67e-82: 295: 24.50		H33_HUMAN (1-136): 1.59e-61: 186: 97.06