HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: S10A4 (P26447)
Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4)
Gene: S100A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 101
+	Hs
		667925 CDK2_HUMAN (1-298): 3.17e-166: 464: 100.00		HORN_HUMAN (1-96): 4.87e-33: 122: 25.74
+	Hs
		667899 CDK2_HUMAN (1-298): 3.17e-166: 464: 100.00		FILA2_HUMAN (3-100): 5.55e-31: 116: 29.13
+	Hs
		445126 CDK2_HUMAN (1-298): 3.17e-166: 464: 100.00		S10A6_HUMAN (1-92): 1.5e-29: 102: 50.00
+	Hs
		424137 CDK2_HUMAN (1-298): 3.17e-166: 464: 100.00		S10A8_HUMAN (1-88): 2e-25: 92.6: 29.55
+	Hs
		443428 CDK1_HUMAN (1-289): 2.35e-143: 407: 66.90		HORN_HUMAN (1-96): 4.87e-33: 122: 25.74
+	Hs
		443396 CDK1_HUMAN (1-289): 2.35e-143: 407: 66.90		FILA2_HUMAN (3-100): 5.55e-31: 116: 29.13
+	Hs
		706094 CDK17_HUMAN (1-296): 1.3e-122: 362: 52.53		S10A2_HUMAN (1-97): 1.09e-36: 121: 60.83
+	Hs
		682476 CDK17_HUMAN (1-296): 1.3e-122: 362: 52.53		S100P_HUMAN (3-96): 4.78e-36: 119: 41.49
+	Hs
		407611 CDK17_HUMAN (1-296): 1.3e-122: 362: 52.53		S100B_HUMAN (3-91): 4.85e-32: 109: 47.19
+	Hs
		954946 CDK16_HUMAN (1-286): 4.12e-107: 322: 55.40		S10AA_HUMAN (1-90): 7.55e-33: 111: 36.67