Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2
Interactor 2: CCNA1 (P78396)
Cyclin-A1
Gene: CCNA1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9041194, 10652300, 14701826, 14681231, 12800980, 8397206, 12190313, 9636170, 7799941, 12191604, 8565853, 11264176, 10559988, 19858290, 16159883, 19423708, 15601848, 12970441, 15583032, 16009130 and 1 others
more... |
| Identification Methods | two hybrid, enzymatic study, affinity chromatography technology, biochemical, x-ray crystallography, pull down, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cyclin_C~Pkinase, Cyclin_N~Pkinase |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
