HitPredict

Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: PMS1 (P54277)
PMS1 protein homolog 1 (DNA mismatch repair protein PMS1)
Gene: PMS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34795231
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 882 Hs			1 932
+	Hs
		668482 PML_HUMAN (1-882): 0: 902: 100.00		MLH1_HUMAN (1-525): 1e-135: 426: 19.27
+	Hs
		668543 PML_HUMAN (1-882): 0: 902: 100.00		PMS2_HUMAN (1-580): 8.15e-124: 397: 22.76
+	Hs
		164361 TRI66_HUMAN (29-540): 6.56e-63: 233: 14.31		MLH1_HUMAN (1-525): 1e-135: 426: 19.27
+	Hs
		164498 TRI66_HUMAN (29-540): 6.56e-63: 233: 14.31		MLH3_HUMAN (1-478): 1.73e-122: 407: 21.44
+	Dm
		54712 A8WHL4_DROME (1-543): 1.51e-57: 216: 15.45		A1ZA03_DROME (1-395): 5.02e-119: 386: 28.21
+	Dm
		283831 Q9U3Y7_DROME (1-543): 3.2e-56: 212: 14.89		O76417_DROME (1-395): 3.69e-112: 367: 29.20