Protein: PBX2
Pre-B-cell leukemia transcription factor 2 (Homeobox protein PBX2) (Protein G17)

Gene: PBX2
Organism: Homo sapiens
Interactions: 82
UniProt ID: P40425

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001654 - eye development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

823874

PKNX1
Homeobox protein PKNOX1

6

19

Small-scale

0.945

High

163416

MEIS2
Homeobox protein Meis2

4

19

High-throughput

0.892

High

253006

LMX1B
LIM homeobox transcription factor 1-beta

3

10

High-throughput

0.861

High

478661

HXB5
Homeobox protein Hox-B5

2

20

High-throughput

0.783

High

634830

HXA5
Homeobox protein Hox-A5

2

20

High-throughput

0.783

High

725026

HXC8
Homeobox protein Hox-C8

2

20

High-throughput

0.783

High

725131

HXC9
Homeobox protein Hox-C9

2

20

High-throughput

0.783

High

823878

HXC5
Homeobox protein Hox-C5

2

20

High-throughput

0.783

High

725216

TLX1
T-cell leukemia homeobox protein 1

2

20

Small-scale

0.757

High

724989

HXA9
Homeobox protein Hox-A9

1

20

Small-scale

0.747

High

823872

HXA1
Homeobox protein Hox-A1

1

20

High-throughput

0.740

High

184764

SHOX
Short stature homeobox protein

1

20

High-throughput

0.691

High

823879

HME1
Homeobox protein engrailed-1

1

20

High-throughput

0.691

High

823906

PKNX2
Homeobox protein PKNOX2

1

19

High-throughput

0.691

High

823912

PBX4
Pre-B-cell leukemia transcription factor 4

1

19

High-throughput

0.691

High

823870

MAGA1
Melanoma-associated antigen 1

3

7

High-throughput

0.667

High

823884

MB211
Putative nucleotidyltransferase MAB21L1

3

9

High-throughput

0.667

High

823924

MB212
Protein mab-21-like 2

3

9

High-throughput

0.667

High

823876

WDR4
tRNA

2

4

High-throughput

0.628

High

209961

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.618

High

823875

GSC
Homeobox protein goosecoid

1

20

High-throughput

0.618

High

823892

RIPP2
Protein ripply2

2

2

High-throughput

0.615

High

253536

MUSC
Musculin

2

5

High-throughput

0.606

High

823891

BRM1L
Breast cancer metastasis-suppressor 1-like protein

2

7

High-throughput

0.606

High

823904

CDA7L
Cell division cycle-associated 7-like protein

2

1

High-throughput

0.606

High

823909

ZN587
Zinc finger protein 587

2

1

High-throughput

0.606

High

823822

PBX1
Pre-B-cell leukemia transcription factor 1

1

20

Small-scale

0.584

High

823889

ZCPW2
Zinc finger CW-type PWWP domain protein 2

2

0

High-throughput

0.580

High

138812

STK25
Serine/threonine-protein kinase 25

2

1

High-throughput

0.574

High

139388

VMA5A
von Willebrand factor A domain-containing protein 5A

2

5

High-throughput

0.574

High

823893

F222A
Protein FAM222A

2

5

High-throughput

0.574

High

823897

CE024
UPF0461 protein C5orf24

2

5

High-throughput

0.574

High

823900

DAAF8
Dynein axonemal assembly factor 8

2

5

High-throughput

0.574

High

823905

CC120
Coiled-coil domain-containing protein 120

2

6

High-throughput

0.574

High

823919

TMOD3
Tropomodulin-3

2

3

High-throughput

0.574

High

823925

SRPRB
Signal recognition particle receptor subunit beta

2

2

High-throughput

0.574

High

823885

BFSP2
Phakinin

2

1

High-throughput

0.553

High

823890

EFHC1
EF-hand domain-containing protein 1

2

1

High-throughput

0.553

High

823898

LIPB1
Liprin-beta-1

2

3

High-throughput

0.553

High

823899

F90A1
Protein FAM90A1

2

2

High-throughput

0.553

High

823902

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

2

1

High-throughput

0.553

High

823873

TTC3
E3 ubiquitin-protein ligase TTC3

1

1

High-throughput

0.541

High

133092

FOXE1
Forkhead box protein E1

1

14

High-throughput

0.536

High

221923

FOXS1
Forkhead box protein S1

1

14

High-throughput

0.536

High

593039

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

High-throughput

0.536

High

823871

SOX2
Transcription factor SOX-2

1

12

High-throughput

0.536

High

823882

FOXC1
Forkhead box protein C1

1

15

High-throughput

0.536

High

823887

FHL2
Four and a half LIM domains protein 2

1

3

High-throughput

0.536

High

823895

FOXI2
Forkhead box protein I2

1

12

High-throughput

0.536

High

823918

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

4

High-throughput

0.536

High

823913

CARD9
Caspase recruitment domain-containing protein 9

1

2

High-throughput

0.523

High

823916

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.513

High

287250

RF1M
Peptide chain release factor 1, mitochondrial

1

1

High-throughput

0.489

High

823920

COKA1

1

1

High-throughput

0.489

High

606357

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

823880

SUH
Recombining binding protein suppressor of hairless

1

2

High-throughput

0.479

High

823881

NFIA
Nuclear factor 1 A-type

1

10

High-throughput

0.479

High

823886

CUL3
Cullin-3

1

1

High-throughput

0.479

High

823888

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

Small-scale

0.479

High

823901

SP7
Transcription factor Sp7

1

7

High-throughput

0.479

High

823907

CIC
Protein capicua homolog

1

12

High-throughput

0.479

High

823910

FEV
Protein FEV

1

3

High-throughput

0.479

High

823911

TBX5
T-box transcription factor TBX5

1

13

High-throughput

0.479

High

789068

NUP62
Nuclear pore glycoprotein p62

1

3

Small-scale

0.457

High

823896

CSN6
COP9 signalosome complex subunit 6

1

2

Small-scale

0.457

High

823903

MCRS1
Microspherule protein 1

1

1

Small-scale

0.457

High

327560

ELP1
Elongator complex protein 1

1

0

Small-scale

0.438

High

784979

RL4
Large ribosomal subunit protein uL4

1

0

Small-scale

0.438

High

823869

MTREX
Exosome RNA helicase MTR4

1

0

Small-scale

0.438

High

823914

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

0

Small-scale

0.438

High

823883

TRAF1
TNF receptor-associated factor 1

1

5

Small-scale

0.437

High

823894

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.437

High

64527

CC88B
Coiled-coil domain-containing protein 88B

1

3

Small-scale

0.417

High

823877

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

1

1

Small-scale

0.417

High

823917

ZDHC7
Palmitoyltransferase ZDHHC7

1

1

Small-scale

0.417

High

823922

BAIP2
BAR/IMD domain-containing adapter protein 2

1

2

Small-scale

0.417

High

63746

KRBA1
Protein KRBA1

2

0

High-throughput

0.328

High

823915

PKHA1
Pleckstrin homology domain-containing family A member 1

2

0

High-throughput

0.328

High

823921

AFF4
AF4/FMR2 family member 4

2

0

High-throughput

0.328

High

823923

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.279

Low

298145

DCTN3
Dynactin subunit 3

1

0

Small-scale

0.238

Low

823908

KS6C1
Ribosomal protein S6 kinase delta-1

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025