Protein: TF2LY
Homeobox protein TGIF2LY (TGF-beta-induced transcription factor 2-like protein) (TGFB-induced factor 2-like protein, Y-linked) (TGIF-like on the Y)

Gene: TF2LY, TGIF2LY
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q8IUE0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1307231

TF2LX
Homeobox protein TGIF2LX

3

20

High-throughput

0.855

High

1307249

OGFR
Opioid growth factor receptor

3

3

High-throughput

0.662

High

1152918

NAB2
NGFI-A-binding protein 2

3

0

High-throughput

0.646

High

274186

ANR17
Ankyrin repeat domain-containing protein 17

2

3

High-throughput

0.628

High

1307242

CRBN
Protein cereblon

2

1

High-throughput

0.628

High

1307248

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

2

3

High-throughput

0.628

High

230053

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

3

1

High-throughput

0.604

High

274891

LRP5
Low-density lipoprotein receptor-related protein 5

3

1

High-throughput

0.604

High

287584

LRP6
Low-density lipoprotein receptor-related protein 6

3

1

High-throughput

0.604

High

284332

GEMI
Geminin

2

0

High-throughput

0.602

High

1198186

PDCD4
Programmed cell death protein 4

2

0

High-throughput

0.602

High

1307240

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

2

0

High-throughput

0.602

High

1307251

ARI1
E3 ubiquitin-protein ligase ARIH1

2

0

High-throughput

0.602

High

1307239

SAHH3
Adenosylhomocysteinase 3

2

1

High-throughput

0.574

High

1307243

DPYL5
Dihydropyrimidinase-related protein 5

2

1

High-throughput

0.574

High

1307232

ANKH1
Ankyrin repeat and KH domain-containing protein 1

2

3

High-throughput

0.558

High

1307246

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.549

High

572052

TRI27
Zinc finger protein RFP

1

1

High-throughput

0.536

High

320715

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.513

High

1158676

DPYL2
Dihydropyrimidinase-related protein 2

1

1

High-throughput

0.489

High

1247793

KLH24
Kelch-like protein 24

1

1

High-throughput

0.489

High

1307237

HAUS1
HAUS augmin-like complex subunit 1

1

1

High-throughput

0.489

High

485675

RU2A
U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.479

High

691211

1433T
14-3-3 protein theta

1

2

High-throughput

0.479

High

990457

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.445

High

708908

T2EA
General transcription factor IIE subunit 1

1

0

High-throughput

0.426

High

1307245

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

0

High-throughput

0.426

High

96879

E9PDP5
Ankyrin repeat and KH domain containing 1

1

2

High-throughput

0.407

High

116503

H7C0V5
ANKHD1-EIF4EBP3 readthrough

1

4

High-throughput

0.407

High

1258771

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.407

High

1307234

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

1

1

High-throughput

0.407

High

1307235

DLG5
Disks large homolog 5

1

1

High-throughput

0.407

High

64715

PGP
Glycerol-3-phosphate phosphatase

3

0

High-throughput

0.345

High

539887

RALB
Ras-related protein Ral-B

2

0

High-throughput

0.328

High

1307233

THNS1
Threonine synthase-like 1

2

0

High-throughput

0.328

High

1307236

IRGQ
Immunity-related GTPase family Q protein

2

0

High-throughput

0.328

High

1307247

DCA16
DDB1- and CUL4-associated factor 16

2

0

High-throughput

0.328

High

1307244

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

0

High-throughput

0.282

High

1277299

NT2NA
Notch homolog 2 N-terminal-like protein A

1

0

High-throughput

0.279

Low

1307238

REPS1
RalBP1-associated Eps domain-containing protein 1

1

0

High-throughput

0.279

Low

293965

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.232

Low

1154227

TBCC
Tubulin-specific chaperone C

1

0

High-throughput

0.232

Low

1307241

GPX7
Glutathione peroxidase 7

1

0

High-throughput

0.232

Low

1307250

NISCH
Nischarin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025