HitPredict

Interactor 1: GNA11 (P29992)
Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha)
Gene: GNA11

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 530
+	Hs
		837635 GNAQ_HUMAN (1-359): 1.3e-168: 475: 90.25		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		391440 GNAI2_HUMAN (7-358): 4.41e-161: 456: 50.14		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		444767 GNAI3_HUMAN (7-358): 1.15e-160: 455: 50.57		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369048 GNA11_HUMAN (1-359): 1.18e-165: 468: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1053419 GNA13_HUMAN (8-358): 1.24e-143: 413: 45.00		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		487925 GNAQ_HUMAN (1-359): 1.3e-168: 475: 90.25		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		414479 GNAI1_HUMAN (7-358): 3.66e-163: 462: 51.70		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		487312 GNAI1_HUMAN (7-358): 3.66e-163: 462: 51.70		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		444652 GNAI3_HUMAN (7-358): 1.15e-160: 455: 50.57		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487311 GNAS2_HUMAN (7-359): 3.68e-148: 425: 38.83		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59