Protein: EDE1
EH domain-containing and endocytosis protein 1 (Bud site selection protein 15)

Gene: EDE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 75
UniProt ID: P34216

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005934 - cellular bud tip
GO:0005935 - cellular bud neck

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509480

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

7

16

Small-scale

0.962

High

757690

EDE1
EH domain-containing and endocytosis protein 1

4

16

Small-scale

0.878

High

709344

HRR25
Casein kinase I homolog HRR25

4

0

Small-scale

0.862

High

757693

AKL1
Serine/threonine-protein kinase AKL1

2

16

High-throughput

0.799

High

649598

KCC2
Calcium/calmodulin-dependent protein kinase II

2

1

High-throughput

0.776

High

678088

SYP1
Suppressor of yeast profilin deletion

9

5

Small-scale

0.755

High

646358

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.691

High

665803

KPC1
Protein kinase C-like 1

1

7

High-throughput

0.691

High

602391

PHO85
Cyclin-dependent protein kinase PHO85

1

9

High-throughput

0.647

High

656414

KC11
Casein kinase I homolog 1

1

4

High-throughput

0.647

High

692322

KCC1
Calcium/calmodulin-dependent protein kinase I

1

1

High-throughput

0.647

High

748817

SWE1
Mitosis inhibitor protein kinase SWE1

1

20

High-throughput

0.647

High

757701

PRK1
Actin-regulating kinase PRK1

1

13

Small-scale

0.647

High

757722

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

10

High-throughput

0.647

High

757694

ATG8
Autophagy-related protein 8

2

3

Small-scale

0.639

High

757727

PAL1
Protein PAL1

3

0

Small-scale

0.638

High

751841

SLA2
Protein SLA2

2

19

High-throughput

0.621

High

744817

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

2

6

Small-scale

0.613

High

757717

AP18B
Clathrin coat assembly protein AP180B

2

14

Small-scale

0.595

High

757704

BNI1
Protein BNI1

2

4

Small-scale

0.594

High

364456

CDK1
Cyclin-dependent kinase 1

1

8

High-throughput

0.575

High

757729

PSH1
RING finger protein PSH1

2

5

High-throughput

0.558

High

523524

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.552

High

526323

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

544360

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.552

High

449104

CALM
Calmodulin

1

2

High-throughput

0.536

High

757732

DUF1
DUB-associated factor 1

1

5

High-throughput

0.536

High

670549

SIS1
Protein SIS1

2

2

High-throughput

0.533

High

757712

SGM1
Protein SGM1

2

17

Small-scale

0.533

High

757731

ENT1
Epsin-1

1

15

Small-scale

0.527

High

517972

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.501

High

757696

ETP1
RING finger protein ETP1

1

5

High-throughput

0.481

High

757697

END3
Actin cytoskeleton-regulatory complex protein END3

1

18

High-throughput

0.481

High

757713

PALH
pH-response regulator protein palH/RIM21

1

0

Small-scale

0.480

High

679543

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

691601

AP2B
AP-2 complex subunit beta

1

20

Small-scale

0.479

High

757691

TSA1
Peroxiredoxin TSA1

1

3

Small-scale

0.479

High

757692

AP2A
AP-2 complex subunit alpha

1

20

Small-scale

0.479

High

757695

ECM29
Proteasome component ECM29

1

2

High-throughput

0.479

High

757710

AIP1
Actin-interacting protein 1

1

5

High-throughput

0.479

High

757720

NUM1
Nuclear migration protein NUM1

1

17

High-throughput

0.479

High

757723

TOM1
E3 ubiquitin-protein ligase TOM1

1

5

High-throughput

0.479

High

757700

SEC9
Protein transport protein SEC9

1

0

High-throughput

0.460

High

757702

BUD6
Bud site selection protein 6

1

0

Small-scale

0.460

High

757705

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.460

High

403437

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.445

High

597104

BIP
Endoplasmic reticulum chaperone BiP

1

9

High-throughput

0.445

High

741289

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

757715

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.445

High

678264

ARE1
Sterol O-acyltransferase 1

1

1

High-throughput

0.439

High

757709

RSC8
Chromatin structure-remodeling complex protein RSC8

1

1

High-throughput

0.439

High

706692

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

708707

TF3B
Transcription factor IIIB 70 kDa subunit

1

3

High-throughput

0.437

High

757706

PXA1
Peroxisomal long-chain fatty acid import protein 2

1

2

Small-scale

0.437

High

757708

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

8

High-throughput

0.437

High

757716

NUP42
Nucleoporin NUP42

1

1

High-throughput

0.437

High

757719

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

757721

MLP1
Protein MLP1

1

16

High-throughput

0.437

High

757724

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.437

High

427210

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.426

High

757699

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

0

High-throughput

0.426

High

757703

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.426

High

757711

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.269

Low

757728

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.261

Low

743858

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.251

Low

757698

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

513663

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

757707

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

757714

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

757718

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.249

Low

757725

RSE1
Pre-mRNA-splicing factor RSE1

1

0

High-throughput

0.249

Low

757726

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.249

Low

757730

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

570233

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025