HitPredict

Interactor 1: ABTB3 (A6QL63)
Ankyrin repeat- and BTB/POZ domain-containing protein 3 (BTB/POZ domain-containing protein 11)
Gene: ABTB3

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	35563538, 37788672
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Cullin, BTB~Cullin
Common GO terms	GO:0016020 - membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1104 Hs			1 768
+	Hs
		1113709 ABTB2_HUMAN (10-674): 3.31e-89: 311: 23.24		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		177215 ANR28_HUMAN (166-782): 1.76e-67: 249: 12.65		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1091393 ANK3_HUMAN (492-1060): 6.96e-62: 234: 14.95		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114459 KLH28_HUMAN (891-1094): 7.78e-64: 229: 22.33		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114702 KLH20_HUMAN (892-1094): 2.32e-63: 228: 20.49		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114756 IPP_HUMAN (891-1081): 2e-57: 211: 21.88		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113267 KLH12_HUMAN (901-1094): 1.67e-57: 210: 20.41		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113639 KBTB2_HUMAN (903-1080): 1.06e-49: 189: 24.73		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		329142 RCBT2_HUMAN (887-1069): 2.88e-47: 180: 22.04		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113732 RCBT1_HUMAN (889-1067): 2.32e-37: 150: 17.78		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Dm
		1304395 KLHDB_DROME (893-1094): 1.37e-61: 224: 21.08		Q8IP45_DROME (17-768): 0: 857: 69.08
+	At
		84398 ABAP1_ARATH (865-1076): 6.23e-55: 206: 26.61		CUL3A_ARATH (9-768): 0: 841: 51.45
+	Hs
		1091394 ANK3_HUMAN (492-1060): 6.96e-62: 234: 14.95		CUL4A_HUMAN (10-768): 0: 801: 38.32
+	At
		84394 ABAP1_ARATH (865-1076): 6.23e-55: 206: 26.61		CUL3B_ARATH (9-768): 0: 826: 50.92
+	Hs
		1115232 KLH12_HUMAN (901-1094): 1.67e-57: 210: 20.41		CUL4B_HUMAN (5-768): 0: 796: 36.77
+	Dm
		1047180 KELC_DROME (914-1078): 4.62e-31: 134: 22.42		Q8IP45_DROME (17-768): 0: 857: 69.08
+	Hs
		1112525 KLH12_HUMAN (901-1094): 1.67e-57: 210: 20.41		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		1112605 RCBT1_HUMAN (889-1067): 2.32e-37: 150: 17.78		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		1112922 RCBT1_HUMAN (889-1067): 2.32e-37: 150: 17.78		CUL2_HUMAN (30-768): 0: 673: 26.17
+	Hs
		1336713 RCBT1_HUMAN (889-1067): 2.32e-37: 150: 17.78		CUL5_HUMAN (25-768): 0: 597: 23.77