HitPredict

Interactor 1: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Interactor 2: TAF3 (Q5VWG9)
Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140)
Gene: TAF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31753913, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 801 Hs			1 929
+	Hs
		1141166 BRD3_HUMAN (53-764): 8.33e-122: 384: 56.56		TAF3_HUMAN (1-914): 1.58e-90: 310: 100.00
+	Hs
		674299 BRD2_HUMAN (1-773): 1.65e-170: 514: 100.00		RSF1_HUMAN (170-915): 7.39e-37: 152: 10.27
+	Hs
		674162 BRD2_HUMAN (1-773): 1.65e-170: 514: 100.00		MDC1_HUMAN (114-869): 3.79e-29: 128: 10.85
+	Hs
		674271 BRD2_HUMAN (1-773): 1.65e-170: 514: 100.00		TITIN_HUMAN (66-799): 9.25e-17: 88.3: 10.60
+	Hs
		1141264 BRD3_HUMAN (53-764): 8.33e-122: 384: 56.56		CHAP1_HUMAN (119-736): 1.05e-38: 157: 12.24
+	Hs
		1141275 BRD3_HUMAN (53-764): 8.33e-122: 384: 56.56		RSF1_HUMAN (170-915): 7.39e-37: 152: 10.27
+	Hs
		1129599 BRD3_HUMAN (53-764): 8.33e-122: 384: 56.56		MDC1_HUMAN (114-869): 3.79e-29: 128: 10.85
+	Hs
		1141173 BRD3_HUMAN (53-764): 8.33e-122: 384: 56.56		NIPBL_HUMAN (274-754): 7.07e-10: 65.4: 16.73
+	Hs
		1141227 BRD3_HUMAN (53-764): 8.33e-122: 384: 56.56		THOC2_HUMAN (339-641): 7.85e-10: 65.4: 20.26
+	Hs
		1218890 KAT2A_HUMAN (293-452): 1.67e-30: 131: 26.71		TAF3_HUMAN (1-914): 1.58e-90: 310: 100.00
+	Hs
		260072 BRD4_HUMAN (291-641): 4.15e-23: 108: 17.38		TAF3_HUMAN (1-914): 1.58e-90: 310: 100.00
+	Hs
		259978 BRD4_HUMAN (291-641): 4.15e-23: 108: 17.38		PLEC_HUMAN (30-873): 1.04e-78: 283: 10.21
+	Hs
		1067626 EP300_HUMAN (31-183): 5.55e-39: 159: 30.72		RSF1_HUMAN (170-915): 7.39e-37: 152: 10.27
+	Hs
		1067330 EP300_HUMAN (31-183): 5.55e-39: 159: 30.72		MDC1_HUMAN (114-869): 3.79e-29: 128: 10.85
+	Hs
		260307 BRD4_HUMAN (291-641): 4.15e-23: 108: 17.38		CHAP1_HUMAN (119-736): 1.05e-38: 157: 12.24
+	Hs
		161457 EP300_HUMAN (31-183): 5.55e-39: 159: 30.72		KMT2D_HUMAN (74-884): 1.7e-16: 87.1: 9.71
+	Hs
		259949 BRD4_HUMAN (291-641): 4.15e-23: 108: 17.38		MDC1_HUMAN (114-869): 3.79e-29: 128: 10.85
+	Hs
		1341029 BRD7_HUMAN (25-283): 2.94e-29: 126: 17.28		THOC2_HUMAN (339-641): 7.85e-10: 65.4: 20.26
+	Hs
		260085 BRD4_HUMAN (291-641): 4.15e-23: 108: 17.38		NIPBL_HUMAN (274-754): 7.07e-10: 65.4: 16.73
+	Hs
		260196 BRD4_HUMAN (291-641): 4.15e-23: 108: 17.38		THOC2_HUMAN (339-641): 7.85e-10: 65.4: 20.26