Interactor 1: GCH1 (P30793)
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)
Gene: GCH1

Interactor 2: GCH1 (P30793)
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)
Gene: GCH1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.829

The method score is based on:

Property Details
Experiments 16696853, 2463916, 11087827
Identification Methods two hybrid, biochemical, x-ray crystallography
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP_cyclohydroI~GTP_cyclohydroI
Common GO terms GO:0003924 - GTPase activity
GO:0003934 - GTP cyclohydrolase I activity
GO:0005509 - calcium ion binding
GO:0005525 - GTP binding
GO:0005634 - nucleus
and 36 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 250
Hs

1 250
+ Rn
+ Sc
+ Ce
+ Dm
+ Hp
+ Ec
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024