HitPredict

Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RhoGAP~SH3_1, PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2087 Hs			1 512
+	Hs
		67608 RHG32_HUMAN (1-2087): 0: 1431: 100.00		SRC_HUMAN (1-510): 0: 591: 51.97
+	Hs
		67601 RHG32_HUMAN (1-2087): 0: 1431: 100.00		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		67602 RHG32_HUMAN (1-2087): 0: 1431: 100.00		FYN_HUMAN (1-510): 0: 583: 54.31
+	Hs
		156400 RHG33_HUMAN (74-1286): 1.7e-113: 396: 30.65		FYN_HUMAN (1-510): 0: 583: 54.31
+	Mm
		813524 RHG33_MOUSE (73-1292): 8.72e-113: 394: 31.02		FYN_MOUSE (1-510): 0: 583: 54.12
+	Hs
		463636 RHG12_HUMAN (312-568): 5.97e-71: 258: 28.68		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		463571 RHG21_HUMAN (88-1174): 1.44e-66: 252: 12.42		LYN_HUMAN (1-512): 0: 621: 100.00
+	Hs
		557346 RHG17_HUMAN (189-1023): 4.13e-69: 254: 14.85		SRC_HUMAN (1-510): 0: 591: 51.97
+	Hs
		557237 OCRL_HUMAN (86-543): 7.07e-68: 250: 14.41		SRC_HUMAN (1-510): 0: 591: 51.97
+	Hs
		440117 RHG17_HUMAN (189-1023): 4.13e-69: 254: 14.85		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		440109 RHG21_HUMAN (88-1174): 1.44e-66: 252: 12.42		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		557256 RHG01_HUMAN (188-572): 3.19e-70: 245: 18.09		SRC_HUMAN (1-510): 0: 591: 51.97
+	Hs
		440032 OCRL_HUMAN (86-543): 7.07e-68: 250: 14.41		LCK_HUMAN (1-512): 0: 585: 63.62
+	Hs
		440497 OCRL_HUMAN (86-543): 7.07e-68: 250: 14.41		FYN_HUMAN (1-510): 0: 583: 54.31
+	Hs
		463062 OCRL_HUMAN (86-543): 7.07e-68: 250: 14.41		YES_HUMAN (1-510): 0: 581: 54.26
+	Hs
		362308 RHG17_HUMAN (189-1023): 4.13e-69: 254: 14.85		ABL1_HUMAN (32-509): 1.52e-174: 523: 37.88
+	Ce
		234033 TG325_CAEEL (321-566): 1.25e-63: 236: 29.04		SRC2_CAEEL (1-510): 0: 537: 45.74
+	Hs
		362269 ABR_HUMAN (350-569): 8.46e-67: 246: 32.89		ABL1_HUMAN (32-509): 1.52e-174: 523: 37.88
+	Hs
		362420 3BP1_HUMAN (368-686): 3.88e-64: 235: 25.94		ABL1_HUMAN (32-509): 1.52e-174: 523: 37.88
+	Hs
		1054119 RHG17_HUMAN (189-1023): 4.13e-69: 254: 14.85		BTK_HUMAN (26-505): 7.72e-159: 468: 35.15