HitPredict

Interactor 1: CTR1 (P30825)
High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)
Gene: SLC7A1

Interactor 2: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 629 Hs			1 297
+	Hs
		178409 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		STX7_HUMAN (31-291): 4.47e-50: 167: 23.95
+	Hs
		676569 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		STX12_HUMAN (34-279): 2.35e-49: 166: 25.00
+	Hs
		854881 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		STX4_HUMAN (1-297): 3e-70: 221: 100.00
+	Hs
		178447 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		STX7_HUMAN (31-291): 4.47e-50: 167: 23.95
+	Hs
		966060 LAT1_HUMAN (22-440): 6.07e-94: 300: 20.24		STX4_HUMAN (1-297): 3e-70: 221: 100.00
+	Hs
		1017841 S12A6_HUMAN (4-490): 5.77e-88: 298: 11.86		STX4_HUMAN (1-297): 3e-70: 221: 100.00
+	At
		1322659 CAAT6_ARATH (11-614): 1.05e-98: 315: 26.94		SYP31_ARATH (2-292): 1.05e-47: 164: 16.02
+	Sc
		743989 TAT1_YEAST (3-522): 1.78e-96: 310: 13.54		SSO2_YEAST (30-289): 3.74e-47: 161: 24.43
+	Hs
		178489 LAT1_HUMAN (22-440): 6.07e-94: 300: 20.24		STX7_HUMAN (31-291): 4.47e-50: 167: 23.95
+	Hs
		178849 S12A6_HUMAN (4-490): 5.77e-88: 298: 11.86		STX7_HUMAN (31-291): 4.47e-50: 167: 23.95