Protein: VPP2
V-type proton ATPase subunit a, Golgi isoform (V-ATPase a 2 subunit) (Similar to VPH1 protein 1) (V-ATPase 101 kDa subunit) (V-ATPase subunit AC115) (Vacuolar proton translocating ATPase subunit a 2)

Gene: VPP2, STV1
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: P37296

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0000329 - fungal-type vacuole membrane
GO:0005770 - late endosome
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

735709

VA0D
V-type proton ATPase subunit d

5

14

Small-scale

0.906

High

790328

VATH
V-type proton ATPase subunit H

3

3

Small-scale

0.857

High

790333

VATG
V-type proton ATPase subunit G

2

8

Small-scale

0.776

High

740046

VPP1
V-type proton ATPase subunit a, vacuolar isoform

2

7

Small-scale

0.754

High

645813

VATE
V-type proton ATPase subunit E

1

8

Small-scale

0.665

High

726559

VATC
V-type proton ATPase subunit C

1

12

Small-scale

0.665

High

603451

VATA
V-type proton ATPase catalytic subunit A

3

16

Small-scale

0.647

High

780733

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

2

1

High-throughput

0.584

High

790349

ATG9
Autophagy-related protein 9

2

2

High-throughput

0.584

High

663597

VATO
V-type proton ATPase subunit c''

1

9

Small-scale

0.575

High

676540

VATL1
V-type proton ATPase subunit c

1

9

Small-scale

0.575

High

746000

VATL2
V-type proton ATPase subunit c'

1

9

Small-scale

0.575

High

790353

VA0E
V-type proton ATPase subunit e

1

1

Small-scale

0.575

High

790352

ATC4
Phospholipid-transporting ATPase DNF2

2

3

High-throughput

0.561

High

628258

ZRC1
Vacuolar zinc transporter ZRC1

1

4

High-throughput

0.541

High

790340

TMEDA
Endoplasmic reticulum vesicle protein 25

1

0

High-throughput

0.518

High

592182

VATB
V-type proton ATPase subunit B

1

9

Small-scale

0.515

High

743674

VATD
V-type proton ATPase subunit D

1

5

Small-scale

0.515

High

790321

VATF
V-type proton ATPase subunit F

1

6

Small-scale

0.515

High

744959

FRE1
Ferric/cupric reductase transmembrane component 1

1

1

High-throughput

0.494

High

536109

ARF1
ADP-ribosylation factor 1

1

3

Small-scale

0.479

High

582448

SEC23
Protein transport protein SEC23

1

1

High-throughput

0.479

High

646658

VPS15
Serine/threonine-protein kinase VPS15

1

2

High-throughput

0.479

High

744377

ATC5
Phospholipid-transporting ATPase DNF1

1

3

High-throughput

0.479

High

746236

PTM1
Membrane protein PTM1

1

1

High-throughput

0.479

High

751572

SNC2
Synaptobrevin homolog 2

1

5

High-throughput

0.479

High

790312

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

790315

YHB7
Uncharacterized membrane protein YHL071W

1

1

High-throughput

0.479

High

790322

ATC3
Phospholipid-transporting ATPase DRS2

1

4

High-throughput

0.479

High

790327

SEC24
Protein transport protein SEC24

1

1

High-throughput

0.479

High

790337

VOA1
V0 assembly protein 1

1

1

High-throughput

0.479

High

736957

CDC3
Cell division control protein 3

1

0

High-throughput

0.460

High

790317

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

790319

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.460

High

560277

KEX2
Kexin

1

0

High-throughput

0.458

High

649817

VPS34
Phosphatidylinositol 3-kinase VPS34

1

0

High-throughput

0.458

High

743899

GDA1
Guanosine-diphosphatase

1

0

High-throughput

0.458

High

790318

AKR1
Palmitoyltransferase AKR1

1

0

High-throughput

0.458

High

790320

MNN1
Alpha-1,3-mannosyltransferase MNN1

1

0

High-throughput

0.458

High

790330

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.458

High

790341

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.458

High

790345

TVP18
Golgi apparatus membrane protein TVP18

1

0

High-throughput

0.458

High

790348

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

4

Small-scale

0.445

High

665809

KPC1
Protein kinase C-like 1

1

2

High-throughput

0.439

High

735614

SMY1
Kinesin-related protein SMY1

1

1

High-throughput

0.439

High

755226

NUF2
Kinetochore protein NUF2

1

2

High-throughput

0.439

High

790316

LAM4
Membrane-anchored lipid-binding protein LAM4

1

1

High-throughput

0.439

High

544538

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.437

High

705162

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

706841

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

790323

PHO90
Low-affinity phosphate transporter PHO90

1

1

High-throughput

0.437

High

790332

GNP1
High-affinity glutamine permease

1

4

High-throughput

0.437

High

790335

AIM14
Probable metalloreductase AIM14

1

1

High-throughput

0.437

High

790344

SEC13
Protein transport protein SEC13

1

1

High-throughput

0.437

High

477551

MYO1
Myosin-1

1

0

High-throughput

0.251

Low

548199

BIK1
Nuclear fusion protein BIK1

1

0

High-throughput

0.251

Low

617386

GBB
Guanine nucleotide-binding protein subunit beta

1

0

High-throughput

0.251

Low

750633

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.251

Low

779740

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.251

Low

790314

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

790324

LIS1
Nuclear distribution protein PAC1

1

0

High-throughput

0.251

Low

790325

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.251

Low

790326

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.251

Low

790329

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

790331

TEA1
TY1 enhancer activator

1

0

High-throughput

0.251

Low

790334

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.251

Low

790336

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.251

Low

790338

CNM67
Chaotic nuclear migration protein 67

1

0

High-throughput

0.251

Low

790339

AF9
Protein AF-9 homolog

1

0

High-throughput

0.251

Low

790346

MMR1
Mitochondrial MYO2 receptor-related protein 1

1

0

High-throughput

0.251

Low

790351

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.251

Low

790354

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

484286

KEX1
Pheromone-processing carboxypeptidase KEX1

1

0

High-throughput

0.249

Low

712779

CHS3
Chitin synthase 3

1

0

High-throughput

0.249

Low

747184

PMP1
Plasma membrane ATPase proteolipid 1

1

0

High-throughput

0.249

Low

790313

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.249

Low

790342

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

790347

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.249

Low

790343

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low

790350

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025