Protein: VPP4
V-type proton ATPase 116 kDa subunit a 4 (V-ATPase 116 kDa isoform a 4) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform)

Gene: VPP4, ATP6V0A4
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q9HBG4

Gene Ontology (top 5):
GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0001503 - ossification
GO:0005765 - lysosomal membrane
GO:0005768 - endosome
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

637114

VATC1
V-type proton ATPase subunit C 1

2

12

High-throughput

0.737

High

784807

VATE1
V-type proton ATPase subunit E 1

2

8

High-throughput

0.737

High

961571

VA0D1
V-type proton ATPase subunit d 1

2

14

High-throughput

0.737

High

1331449

VA0D2
V-type proton ATPase subunit d 2

2

14

High-throughput

0.737

High

692267

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

9

High-throughput

0.691

High

1402467

MYADM
Myeloid-associated differentiation marker

1

1

High-throughput

0.691

High

1438151

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

7

High-throughput

0.691

High

292748

RENR
Renin receptor

2

5

High-throughput

0.601

High

1155270

VAS1
V-type proton ATPase subunit S1

2

6

High-throughput

0.601

High

1164272

VATF
V-type proton ATPase subunit F

2

6

High-throughput

0.601

High

1327055

VMA12
Vacuolar ATPase assembly protein VMA12

2

6

High-throughput

0.601

High

1399172

VMA22
Vacuolar ATPase assembly protein VMA22

2

3

High-throughput

0.601

High

1438152

VATD
V-type proton ATPase subunit D

2

5

High-throughput

0.601

High

1381837

VATE2
V-type proton ATPase subunit E 2

1

8

High-throughput

0.575

High

583107

VATB1
V-type proton ATPase subunit B, kidney isoform

2

9

Small-scale

0.571

High

637068

VATB2
V-type proton ATPase subunit B, brain isoform

2

9

High-throughput

0.571

High

467965

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

0

Small-scale

0.537

High

899677

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

1

1

High-throughput

0.536

High

369092

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.513

High

772417

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

High-throughput

0.513

High

1106080

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.513

High

1404083

CYH2
Cytohesin-2

1

4

Small-scale

0.501

High

387465

APOE
Apolipoprotein E

1

0

High-throughput

0.493

High

1191800

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

3

High-throughput

0.489

High

178400

NPC1
NPC intracellular cholesterol transporter 1

1

4

High-throughput

0.479

High

1438149

MUC5B
Mucin-5B

1

3

High-throughput

0.445

High

1310792

CUL9
Cullin-9

1

1

High-throughput

0.437

High

370117

CYTS
Cystatin-S

1

0

High-throughput

0.426

High

1387163

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.426

High

1315484

K2013
Uncharacterized protein KIAA2013

1

6

High-throughput

0.407

High

1290369

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.279

Low

1438150

HYPK
Huntingtin-interacting protein K

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025