Interactor 1: KAP1 (P31321)
cAMP-dependent protein kinase type I-beta regulatory subunit
Gene: PRKAR1B

Interactor 2: KAP3 (P31323)
cAMP-dependent protein kinase type II-beta regulatory subunit
Gene: PRKAR2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains cNMP_binding~cNMP_binding, RIIa~RIIa
Common GO terms GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005952 - cAMP-dependent protein kinase complex
GO:0008603 - cAMP-dependent protein kinase regulator activity
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 381
Hs

1 418
+ Hs
+ Sc
+ Mm
+ Mm
+ Ce
+ Sp
+ Hs
+ Hs
+ Mm
+ Mm
+ Bt
+ Hs
+ Dm
+ Zm
+ Dm
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024