HitPredict

Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: TSC2 (P49815)
Tuberin (Tuberous sclerosis 2 protein)
Gene: TSC2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 15342917, 18411301
Identification Methods affinity chromatography technology, protein kinase assay
Interaction Type physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006469 - negative regulation of protein kinase activity
GO:0006606 - protein import into nucleus
and 5 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 480
Hs

1 1807
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024