Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1
Interactor 2: FRDA (Q16595)
Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN); Extramitochondrial frataxin]
Gene: FXN
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 0.55 | 0.480 |
The method score is based on:
Property | Details |
---|---|
Experiments | 34941261 |
Identification Methods | enzymatic study |
Interaction Type | direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0030307 - positive regulation of cell growth GO:0043066 - negative regulation of apoptotic process GO:0090201 - negative regulation of release of cytochrome c from mitochondria |
Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024