HitPredict

Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: MTUS2 (Q5JR59)
Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa)
Gene: MTUS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	26871637
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0015630 - microtubule cytoskeleton GO:0042803 - protein homodimerization activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 1369
+	Hs
		551616 AKT1_HUMAN (1-480): 0: 586: 100.00		DESP_HUMAN (972-1329): 6.4e-13: 76: 15.94
+	Hs
		681696 AKT1_HUMAN (1-480): 0: 586: 100.00		MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70
+	Mm
		554927 KPCE_MOUSE (53-474): 8.58e-146: 436: 39.53		MYH7_MOUSE (1006-1369): 1.38e-18: 94.9: 14.56
+	Hs
		528359 KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86		MYH6_HUMAN (726-1318): 6.46e-24: 112: 11.52
+	Dm
		397193 KPC1_DROME (14-477): 1.79e-152: 451: 35.91		MYSN_DROME (1046-1345): 6.46e-10: 66.1: 19.17
+	Mm
		554901 KPCE_MOUSE (53-474): 8.58e-146: 436: 39.53		MYH6_MOUSE (813-1229): 2.13e-14: 81: 9.93
+	Hs
		551672 KPCE_HUMAN (53-474): 3.43e-146: 437: 39.77		DESP_HUMAN (972-1329): 6.4e-13: 76: 15.94
+	Hs
		724784 KPCE_HUMAN (53-474): 3.43e-146: 437: 39.77		MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70
+	Hs
		568568 KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53		MYH10_HUMAN (928-1347): 4.52e-17: 89.6: 16.17
+	Hs
		116964 SGK1_HUMAN (104-478): 5.29e-146: 426: 44.97		MYH1_HUMAN (698-1170): 2.35e-14: 81: 7.93
+	Hs
		568732 KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53		NIN_HUMAN (992-1353): 2.45e-14: 80.6: 18.36
+	Hs
		522538 KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86		MYH1_HUMAN (698-1170): 2.35e-14: 81: 7.93
+	Hs
		610749 KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86		NIN_HUMAN (992-1353): 2.45e-14: 80.6: 18.36
+	Hs
		610802 KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86		MYH4_HUMAN (698-1170): 2e-13: 77.9: 8.56
+	Hs
		568567 KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53		MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70
+	Hs
		610795 KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86		MYH2_HUMAN (706-1121): 2.6e-11: 71: 7.43
+	Hs
		254459 KS6A3_HUMAN (36-455): 4.1e-103: 325: 23.01		ROCK2_HUMAN (675-1115): 4.42e-15: 82.9: 9.77
+	Hs
		254504 SGK3_HUMAN (149-447): 5.26e-100: 310: 51.00		ROCK2_HUMAN (675-1115): 4.42e-15: 82.9: 9.77
+	Hs
		1071723 KS6A2_HUMAN (85-452): 6.82e-94: 301: 25.39		MRCKB_HUMAN (1175-1367): 5.39e-15: 82.9: 8.70