HitPredict

Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: BAD (Q92934)
Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)
Gene: BAD

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.750

Property	Details
Experiments	15722337, 10358075, 23085457, 11500364, 11994280, 15998799, 19667065
Identification Methods	enzymatic study, affinity chromatography technology, pull down, protein kinase assay
Interaction Type	direct interaction, physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0019221 - cytokine-mediated signaling pathway GO:0019901 - protein kinase binding GO:0042593 - glucose homeostasis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 168
+	Mm
		682110 AKT1_MOUSE (1-480): 0: 587: 98.33		BAD_MOUSE (1-168): 3.09e-82: 243: 75.00
+	Hs
		566443 KPCA_HUMAN (14-477): 1.41e-151: 448: 36.27		BAD_HUMAN (1-168): 1.17e-91: 265: 100.00
+	Hs
		969099 KPCE_HUMAN (53-474): 3.43e-146: 437: 39.77		BAD_HUMAN (1-168): 1.17e-91: 265: 100.00
+	Hs
		568755 KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53		BAD_HUMAN (1-168): 1.17e-91: 265: 100.00
+	Hs
		610759 KAPCB_HUMAN (138-445): 1.1e-143: 417: 42.86		BAD_HUMAN (1-168): 1.17e-91: 265: 100.00
+	Hs
		784059 KPCI_HUMAN (139-474): 7.46e-101: 316: 45.53		BAD_HUMAN (1-168): 1.17e-91: 265: 100.00
+	Hs
		1073460 KS6A1_HUMAN (85-407): 6.15e-92: 296: 26.39		BAD_HUMAN (1-168): 1.17e-91: 265: 100.00