HitPredict

Interactor 1: HECA2 (A8MVW5)
HEPACAM family member 2 (Mitotic kinetics regulator)
Gene: HEPACAM2

Interactor 2: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ig_3~fn3, Ig_3~I-set
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 1907
+	Hs
		68228 HECA2_HUMAN (1-462): 2.38e-97: 302: 100.00		PTPRS_HUMAN (1-1907): 0: 1581: 65.73
+	Hs
		489970 CEA21_HUMAN (89-237): 1.08e-42: 154: 28.86		PTPRF_HUMAN (1-1907): 0: 1662: 100.00
+	Hs
		685236 CEAM8_HUMAN (14-366): 4.75e-62: 207: 23.10		PTPRS_HUMAN (1-1907): 0: 1581: 65.73
+	Hs
		1031992 CEA21_HUMAN (89-237): 1.08e-42: 154: 28.86		PTPRS_HUMAN (1-1907): 0: 1581: 65.73
+	Mm
		530202 NCAM1_MOUSE (22-461): 2.22e-61: 218: 14.19		PTPRA_MOUSE (1142-1907): 0: 799: 39.09
+	Gg
		47583 CNTN1_CHICK (120-461): 1.01e-34: 140: 12.57		A0A8V0YWD3_CHICK (1153-1907): 0: 814: 42.11
+	Hs
		685250 CEAM8_HUMAN (14-366): 4.75e-62: 207: 23.10		SDK2_HUMAN (165-1102): 1.35e-112: 401: 20.04
+	Hs
		1108780 CEA21_HUMAN (89-237): 1.08e-42: 154: 28.86		SDK2_HUMAN (165-1102): 1.35e-112: 401: 20.04
+	Hs
		617163 CNTN1_HUMAN (121-461): 1.2e-35: 142: 15.03		PTPRZ_HUMAN (1132-1623): 2.35e-47: 190: 19.69
+	Hs
		685244 CEAM8_HUMAN (14-366): 4.75e-62: 207: 23.10		PTPRK_HUMAN (116-656): 8.46e-16: 86.2: 14.41
+	Hs
		616914 CNTN1_HUMAN (121-461): 1.2e-35: 142: 15.03		PTPRB_HUMAN (502-1274): 6.16e-29: 129: 11.67
+	Hs
		1069962 LRIG1_HUMAN (121-434): 1.8e-39: 154: 13.51		PTPRK_HUMAN (116-656): 8.46e-16: 86.2: 14.41
+	Hs
		1069952 PXDN_HUMAN (2-261): 5.14e-39: 152: 17.91		PTPRK_HUMAN (116-656): 8.46e-16: 86.2: 14.41
+	Hs
		441175 CD22_HUMAN (38-437): 2.92e-30: 126: 15.71		PTPRC_HUMAN (362-695): 1.66e-10: 68.5: 14.29