Interactor 1: SMCA5 (O60264)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H)
Gene: SMARCA5

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.-) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 28977666, 24981860, 12198550
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HAND~SNF2-rel_dom, Helicase_C~Helicase_C, Helicase_C~SNF2-rel_dom, Chromo~SNF2-rel_dom, SNF2-rel_dom~SNF2-rel_dom
Common GO terms GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
and 7 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1052
Hs

1 2000
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Last updated: 11Aug2025