HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: TESK2 (Q96S53)
Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2)
Gene: TESK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.921

The method score is based on:

Property Details
Experiments 11555644, 32707033, 33961781, 36931259, 28514442
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~PK_Tyr_Ser-Thr
Common GO terms GO:0005737 - cytoplasm
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 246
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024