HitPredict

Interactor 1: RAB6A (P20340)
Ras-related protein Rab-6A (Rab-6)
Gene: RAB6A

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Hs			1 779
+	Hs
		918949 RAB1A_HUMAN (1-207): 2.16e-92: 270: 35.27		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		592495 RAB5A_HUMAN (3-207): 1.63e-90: 266: 40.00		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		844738 RAB5C_HUMAN (3-207): 7.83e-91: 266: 39.51		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1331390 RAB6B_HUMAN (1-208): 5.58e-90: 264: 90.87		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1328144 RAB1B_HUMAN (9-206): 1.18e-89: 263: 35.86		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		914357 RB11A_HUMAN (3-206): 1.19e-86: 256: 29.58		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		895380 RAB5B_HUMAN (13-178): 1.33e-47: 157: 45.18		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		592584 RAB5A_HUMAN (3-207): 1.63e-90: 266: 40.00		TBD2B_HUMAN (53-512): 3.31e-51: 195: 17.57
+	Hs
		914051 RB11A_HUMAN (3-206): 1.19e-86: 256: 29.58		GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92
+	Hs
		914465 RB11A_HUMAN (3-206): 1.19e-86: 256: 29.58		TBD2B_HUMAN (53-512): 3.31e-51: 195: 17.57
+	Hs
		592656 RAB6A_HUMAN (1-208): 2.17e-89: 263: 100.00		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		914432 RB11A_HUMAN (3-206): 1.19e-86: 256: 29.58		SWP70_HUMAN (55-446): 3.06e-44: 170: 11.36
+	Hs
		592263 RAB5A_HUMAN (3-207): 1.63e-90: 266: 40.00		ACAP2_HUMAN (28-517): 6.24e-39: 156: 13.10
+	Hs
		592506 RAB5A_HUMAN (3-207): 1.63e-90: 266: 40.00		PKHA1_HUMAN (16-261): 3.76e-39: 151: 16.92
+	Hs
		1328146 RAB1B_HUMAN (9-206): 1.18e-89: 263: 35.86		PKHA2_HUMAN (1-258): 2.68e-38: 149: 15.90
+	Ce
		1095338 RAB10_CAEEL (10-206): 1.51e-83: 247: 39.09		Q23419_CAEEL (46-578): 5.81e-41: 163: 12.59
+	Hs
		914370 RB11A_HUMAN (3-206): 1.19e-86: 256: 29.58		PKHA1_HUMAN (16-261): 3.76e-39: 151: 16.92
+	Hs
		914367 RB11A_HUMAN (3-206): 1.19e-86: 256: 29.58		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Dm
		185683 O18335_DROME (3-206): 1.87e-85: 253: 29.11		Q7KS50_DROME (43-198): 1.76e-29: 126: 26.29
+	Dm
		185607 RAB6_DROME (1-208): 1.2e-83: 248: 87.56		Q7KS50_DROME (43-198): 1.76e-29: 126: 26.29