HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: MATK (P42679)
Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)
Gene: MATK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 507
+	Hs
		788960 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MATK_HUMAN (1-507): 0: 559: 100.00
+	Hs
		411616 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		337367 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		683884 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ABL2_HUMAN (13-503): 2.01e-164: 498: 31.37
+	Hs
		683994 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ITK_HUMAN (33-484): 4.01e-169: 493: 33.12
+	Hs
		411661 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		337416 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		782766 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CSK_HUMAN (45-485): 8.23e-174: 498: 53.05
+	Hs
		789053 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ABL2_HUMAN (13-503): 2.01e-164: 498: 31.37
+	Hs
		909481 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ITK_HUMAN (33-484): 4.01e-169: 493: 33.12
+	Hs
		411666 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		337420 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		782768 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		CSK_HUMAN (45-485): 8.23e-174: 498: 53.05
+	Hs
		789056 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ABL2_HUMAN (13-503): 2.01e-164: 498: 31.37
+	Hs
		411605 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		337355 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		646706 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		ABL2_HUMAN (13-503): 2.01e-164: 498: 31.37
+	Hs
		337366 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		683181 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		CSK_HUMAN (45-485): 8.23e-174: 498: 53.05
+	Hs
		683185 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		ABL2_HUMAN (13-503): 2.01e-164: 498: 31.37