HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: SIK3 (Q9Y2K2)
Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)
Gene: SIK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36931259, 22588126
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1321
+	Hs
		647836 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK3_HUMAN (1-694): 4.86e-154: 484: 30.98
+	Hs
		684316 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK2_HUMAN (50-831): 1.65e-151: 483: 34.99
+	Hs
		684157 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK2_HUMAN (15-704): 3.17e-143: 457: 30.38
+	Mm
		910231 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK3_MOUSE (1-694): 2.82e-154: 485: 32.11
+	Hs
		647862 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MARK3_HUMAN (1-694): 4.86e-154: 484: 30.98
+	Hs
		683925 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK1_HUMAN (50-805): 2.9e-138: 443: 31.73
+	Hs
		684349 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SNRK_HUMAN (52-427): 1.48e-137: 441: 38.85
+	Hs
		683920 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		AAPK2_HUMAN (52-589): 2.46e-139: 438: 30.39
+	Hs
		684009 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		AAPK1_HUMAN (44-598): 1.69e-138: 436: 28.91
+	Mm
		910308 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK4_MOUSE (1-716): 7.87e-145: 460: 30.89
+	Hs
		909730 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MARK2_HUMAN (15-704): 3.17e-143: 457: 30.38
+	Mm
		910234 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK2_MOUSE (15-704): 7.86e-143: 455: 30.37
+	Hs
		883214 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SIK1_HUMAN (50-805): 2.9e-138: 443: 31.73
+	Hs
		871354 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		AAPK2_HUMAN (52-589): 2.46e-139: 438: 30.39
+	Hs
		909507 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		AAPK1_HUMAN (44-598): 1.69e-138: 436: 28.91
+	Rn
		871214 1433E_RAT (2-246): 4.41e-146: 410: 60.41		AAPK1_RAT (44-599): 4.74e-138: 435: 28.98
+	Mm
		910318 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK1_MOUSE (35-488): 1.17e-133: 431: 44.35
+	Hs
		684364 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK1_HUMAN (41-382): 1.92e-105: 354: 55.43
+	Hs
		684192 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		BRSK2_HUMAN (63-398): 9.43e-78: 275: 43.49
+	Mm
		910272 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		BRSK2_MOUSE (63-398): 5.78e-78: 275: 43.49