HitPredict

Interactor 1: HMGB2 (P26583)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Interactor 2: CPAP (Q9HC77)
Centrosomal P4.1-associated protein (Centromere protein J) (CENP-J) (Centrosome assembly and centriole elongation protein) (LAG-3-associated protein) (LYST-interacting protein 1)
Gene: CPAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38334954
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005737 - cytoplasm GO:0019904 - protein domain specific binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 209 Hs			1 1338
+	Hs
		1401398 CIC_HUMAN (3-91): 1.53e-11: 64.7: 22.47		CPAP_HUMAN (1-1338): 3.17e-149: 488: 100.00
+	Hs
		687274 HMGB2_HUMAN (1-187): 6.47e-41: 139: 100.00		MY18A_HUMAN (505-1181): 3.94e-21: 103: 10.61
+	Hs
		659173 SP100_HUMAN (25-174): 3.45e-31: 121: 74.67		MYH9_HUMAN (570-1196): 7.95e-21: 102: 8.50
+	Hs
		872350 SOX2_HUMAN (3-94): 1.21e-23: 97.5: 22.83		PLEC_HUMAN (256-1192): 4.91e-28: 125: 6.72
+	Hs
		773125 SOX2_HUMAN (3-94): 1.21e-23: 97.5: 22.83		MYH10_HUMAN (63-774): 1.93e-19: 97.4: 8.65
+	Hs
		587588 SOX2_HUMAN (3-94): 1.21e-23: 97.5: 22.83		DESP_HUMAN (653-1103): 1.51e-09: 64.9: 15.82
+	Mm
		98057 SOX17_MOUSE (4-90): 1.34e-23: 98.6: 21.84		DESP_MOUSE (653-1161): 7.07e-09: 63: 15.63
+	Hs
		587777 CIC_HUMAN (3-91): 1.53e-11: 64.7: 22.47		DESP_HUMAN (653-1103): 1.51e-09: 64.9: 15.82