HitPredict

Interactor 1: HIR2 (P32480)
Protein HIR2 (Histone transcription regulator 2)
Gene: HIR2

Interactor 2: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36269765, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 875 Sc			1 693
+	Sc
		690828 HIR1_YEAST (1-542): 6.88e-84: 288: 17.77		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Hs
		503817 WDR5_HUMAN (4-350): 6.32e-53: 189: 11.68		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Sc
		695455 CAC2_YEAST (63-409): 1.11e-58: 209: 18.80		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Hs
		504344 WDR5B_HUMAN (4-349): 5.83e-52: 186: 11.14		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		503747 HIRA_HUMAN (202-540): 5.57e-28: 123: 10.24		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		503614 LIS1_HUMAN (440-738): 1.31e-19: 94.1: 8.11		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		504412 POC1A_HUMAN (396-732): 7.64e-18: 88.7: 11.14		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		714020 POC1A_HUMAN (396-732): 7.64e-18: 88.7: 11.14		HS71L_HUMAN (2-646): 0: 848: 26.69
+	Hs
		564125 POC1A_HUMAN (396-732): 7.64e-18: 88.7: 11.14		HSP76_HUMAN (4-643): 0: 842: 26.28
+	Hs
		274323 WDHD1_HUMAN (317-549): 1.34e-12: 74.1: 7.38		HSP76_HUMAN (4-643): 0: 842: 26.28
+	Hs
		274338 WDHD1_HUMAN (317-549): 1.34e-12: 74.1: 7.38		HSP72_HUMAN (2-644): 0: 840: 27.08
+	Sp
		251256 SLM9_SCHPO (4-190): 3.68e-14: 78.7: 6.67		HSP71_SCHPO (1-644): 0: 828: 26.88
+	Sc
		493458 HIR2_YEAST (1-875): 0: 583: 100.00		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		490648 HIR2_YEAST (1-875): 0: 583: 100.00		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sp
		223763 SLM9_SCHPO (4-190): 3.68e-14: 78.7: 6.67		HSP7F_SCHPO (6-682): 0: 556: 46.42
+	Sc
		490647 HIR1_YEAST (1-542): 6.88e-84: 288: 17.77		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Zm
		12571 A0A1D6MEH7_MAIZE (501-738): 5.5e-12: 71: 7.79		A0A1D6FNB8_MAIZE (6-647): 4.14e-143: 441: 36.42
+	Sc
		492337 CAC2_YEAST (63-409): 1.11e-58: 209: 18.80		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		494908 SEC13_YEAST (133-397): 3.43e-14: 76.1: 14.95		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		492371 SEC13_YEAST (133-397): 3.43e-14: 76.1: 14.95		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55