HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: SPEG (Q15772)
Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1)
Gene: SPEG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33961781, 23444366, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 3267
+	Hs
		990262 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		SPEG_HUMAN (1-3267): 0: 2117: 100.00
+	Xl
		237423 O57468_XENLA (2-243): 4.55e-144: 404: 64.75		Q804T2_XENLA (2912-3247): 2.45e-114: 384: 22.94
+	Hs
		692031 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MARK3_HUMAN (2912-3224): 1.12e-112: 380: 23.98
+	Mm
		972206 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		MARK3_MOUSE (2912-3224): 1.82e-112: 379: 24.29
+	Hs
		971493 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		KCC2G_HUMAN (2954-3255): 1.58e-113: 376: 27.33
+	Hs
		690752 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MARK3_HUMAN (2912-3224): 1.12e-112: 380: 23.98
+	Mm
		989952 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		MARK3_MOUSE (2912-3224): 1.82e-112: 379: 24.29
+	Hs
		692038 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		MARK3_HUMAN (2912-3224): 1.12e-112: 380: 23.98
+	Hs
		990191 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		KCC2G_HUMAN (2954-3255): 1.58e-113: 376: 27.33
+	Hs
		972105 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		DAPK2_HUMAN (2952-3248): 1.98e-42: 162: 32.80
+	Hs
		212649 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		DAPK3_HUMAN (2955-3241): 7.58e-41: 160: 32.68
+	Hs
		690851 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		DAPK1_HUMAN (2955-3219): 7.95e-39: 162: 34.30
+	Hs
		212635 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		DAPK3_HUMAN (2955-3241): 7.58e-41: 160: 32.68
+	Hs
		971989 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MYLK2_HUMAN (2770-3257): 2.59e-33: 140: 28.57
+	Hs
		971584 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MYLK3_HUMAN (2784-3267): 3.5e-32: 139: 27.20
+	Hs
		691422 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MYLK2_HUMAN (2770-3257): 2.59e-33: 140: 28.57
+	Hs
		691291 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		TITIN_HUMAN (2380-2580): 8.58e-13: 77.4: 10.14
+	Hs
		990550 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		TITIN_HUMAN (2380-2580): 8.58e-13: 77.4: 10.14
+	Hs
		86664 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		B9ZVR7_HUMAN (17-125): 5.63e-11: 70.8: 27.35
+	Hs
		86667 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		B9ZVR7_HUMAN (17-125): 5.63e-11: 70.8: 27.35