HitPredict

Interactor 1: MYO4 (P32492)
Myosin-4 (SWI5-dependent HO expression protein 1)
Gene: MYO4

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.908

Property	Details
Experiments	11805826, 17893244, 16429126, 18175803
Identification Methods	tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Actin~Myosin_head
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1471 Sc			1 375
+	Sc
		585356 MYO2_YEAST (1-1428): 0: 1103: 48.58		ACT_YEAST (1-375): 0: 594: 100.00
+	Sp
		293470 MYO52_SCHPO (2-1448): 0: 985: 35.72		ACT_SCHPO (1-375): 0: 591: 89.60
+	Hs
		892049 MYO10_HUMAN (3-1001): 0: 930: 31.07		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		930011 MYO10_HUMAN (3-1001): 0: 930: 31.07		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Dm
		51919 A1Z6Z9_DROME (1-1444): 0: 895: 30.18		ACT3_DROME (2-375): 0: 593: 87.97
+	Hs
		930015 MYO5C_HUMAN (703-1435): 1.32e-47: 189: 12.71		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		932396 MYO5C_HUMAN (703-1435): 1.32e-47: 189: 12.71		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		724859 MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Rn
		892228 MYH9_RAT (798-1108): 1.44e-09: 65: 12.82		ACTB_RAT (1-375): 0: 601: 88.80
+	Mm
		892205 MYH9_MOUSE (796-1088): 3.95e-09: 63.9: 9.46		ACTB_MOUSE (1-375): 0: 601: 88.80
+	Hs
		724738 MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		724762 MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		724766 MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		724767 MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18		ACTS_HUMAN (2-375): 0: 590: 86.90