Protein: MYCPP
C-myc promoter-binding protein (DENN domain-containing protein 4A)

Gene: MYCPP, DENND4A
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q7Z401

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

730002

1433B
14-3-3 protein beta/alpha

8

20

High-throughput

0.751

High

966534

1433G
14-3-3 protein gamma

6

20

High-throughput

0.735

High

691180

1433T
14-3-3 protein theta

6

20

High-throughput

0.733

High

990415

1433Z
14-3-3 protein zeta/delta

5

20

High-throughput

0.718

High

1049489

1433F
14-3-3 protein eta

5

20

High-throughput

0.716

High

971708

1433E
14-3-3 protein epsilon

4

5

Small-scale

0.697

High

1277700

METL6
tRNA N(3)-cytidine methyltransferase METTL6

3

0

High-throughput

0.638

High

901347

RAB7A
Ras-related protein Rab-7a

1

8

High-throughput

0.618

High

901902

RAB9A
Ras-related protein Rab-9A

1

16

High-throughput

0.618

High

976371

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.618

High

1144983

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.618

High

1219594

DEN4C
DENN domain-containing protein 4C

1

5

High-throughput

0.618

High

1277701

DEN1A
DENN domain-containing protein 1A

1

5

High-throughput

0.618

High

596195

H12
Histone H1.2

2

1

High-throughput

0.584

High

614704

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

2

1

High-throughput

0.574

High

1226963

A16L1
Autophagy-related protein 16-1

2

3

High-throughput

0.571

High

630860

RAB4A
Ras-related protein Rab-4A

1

7

High-throughput

0.553

High

1152982

CEBPE
CCAAT/enhancer-binding protein epsilon

1

1

High-throughput

0.541

High

647590

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

1

High-throughput

0.536

High

682537

S100P
Protein S100-P

1

2

High-throughput

0.536

High

997823

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.536

High

1277699

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1277704

VPS35
Vacuolar protein sorting-associated protein 35

1

1

High-throughput

0.536

High

1277722

ASB3
Ankyrin repeat and SOCS box protein 3

1

3

High-throughput

0.536

High

225041

TLX3
T-cell leukemia homeobox protein 3

1

0

High-throughput

0.518

High

961612

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.518

High

1277718

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.518

High

1085132

SCRN1
Secernin-1

1

0

High-throughput

0.513

High

1093260

FLII
Protein flightless-1 homolog

1

0

High-throughput

0.513

High

1277716

VPS29
Vacuolar protein sorting-associated protein 29

1

0

High-throughput

0.513

High

472853

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.493

High

1277713

INT13
Integrator complex subunit 13

1

0

High-throughput

0.493

High

706189

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

1156984

NTRK3
NT-3 growth factor receptor

1

8

High-throughput

0.489

High

889446

CLK1
Dual specificity protein kinase CLK1

1

0

High-throughput

0.480

High

226100

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

252099

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

2

High-throughput

0.479

High

269574

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

3

High-throughput

0.479

High

281357

GGYF1
GRB10-interacting GYF protein 1

1

5

High-throughput

0.479

High

372416

MYC
Myc proto-oncogene protein

1

3

Small-scale

0.479

High

637915

NF1
Neurofibromin

1

5

High-throughput

0.479

High

730717

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

772877

MYH9
Myosin-9

1

1

High-throughput

0.479

High

891221

GSK3A
Glycogen synthase kinase-3 alpha

1

3

High-throughput

0.479

High

891647

GSK3B
Glycogen synthase kinase-3 beta

1

3

High-throughput

0.479

High

909611

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

1

High-throughput

0.479

High

941005

HDAC4
Histone deacetylase 4

1

6

High-throughput

0.479

High

1029326

SET
Protein SET

1

1

High-throughput

0.479

High

1041145

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1106980

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1133995

ZN638
Zinc finger protein 638

1

2

High-throughput

0.479

High

1141730

EEA1
Early endosome antigen 1

1

2

High-throughput

0.479

High

1216065

SPD2A
SH3 and PX domain-containing protein 2A

1

7

High-throughput

0.479

High

1277697

KSR1
Kinase suppressor of Ras 1

1

5

High-throughput

0.479

High

1277706

TESK2
Dual specificity testis-specific protein kinase 2

1

3

High-throughput

0.479

High

1277707

RTKN
Rhotekin

1

2

High-throughput

0.479

High

1277710

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1277712

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

2

High-throughput

0.479

High

1277717

LIMA1
LIM domain and actin-binding protein 1

1

2

High-throughput

0.479

High

1277719

ZBT21
Zinc finger and BTB domain-containing protein 21

1

2

High-throughput

0.479

High

1277720

PPM1H
Protein phosphatase 1H

1

3

High-throughput

0.479

High

1277721

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.479

High

165365

PSA7
Proteasome subunit alpha type-7

1

0

High-throughput

0.458

High

437243

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

830978

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

973221

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

516353

CALM1
Calmodulin-1

1

6

High-throughput

0.445

High

516427

CALM2
Calmodulin-2

1

6

High-throughput

0.445

High

516546

CALM3
Calmodulin-3

1

6

High-throughput

0.445

High

1258478

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.445

High

176845

DCLK1
Serine/threonine-protein kinase DCLK1

1

3

High-throughput

0.437

High

189663

STX7
Syntaxin-7

1

2

High-throughput

0.437

High

208697

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

2

High-throughput

0.437

High

245245

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

5

High-throughput

0.437

High

293929

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

1233311

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

1276186

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.437

High

1277702

SRS12
Serine/arginine-rich splicing factor 12

1

2

High-throughput

0.437

High

1277705

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

5

High-throughput

0.437

High

1277709

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

1277711

KI13B
Kinesin-like protein KIF13B

1

6

High-throughput

0.437

High

1277714

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

3

High-throughput

0.437

High

1277715

CING
Cingulin

1

4

High-throughput

0.437

High

1277723

KCTD3
BTB/POZ domain-containing protein KCTD3

1

5

High-throughput

0.437

High

1010933

BAT1
b(0,+)-type amino acid transporter 1

1

1

High-throughput

0.407

High

1277698

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

1

High-throughput

0.407

High

1277708

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

1

High-throughput

0.407

High

505834

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

0

High-throughput

0.282

High

348156

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

0

High-throughput

0.279

Low

1248552

LYPD4
Ly6/PLAUR domain-containing protein 4

1

0

High-throughput

0.279

Low

768522

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1277703

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025