HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: KPCD2 (Q9BZL6)
Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2)
Gene: PRKD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 878
+	Hs
		971548 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		KPCD1_HUMAN (17-878): 0: 798: 67.63
+	Hs
		691025 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		KPCD1_HUMAN (17-878): 0: 798: 67.63
+	Hs
		990249 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		KPCD1_HUMAN (17-878): 0: 798: 67.63
+	Hs
		603172 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		KPCA_HUMAN (103-867): 0: 570: 17.67
+	Hs
		603227 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		KPCA_HUMAN (103-867): 0: 570: 17.67
+	Hs
		424652 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		KPCG_HUMAN (124-867): 3.57e-178: 532: 17.35
+	Hs
		728147 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		AKT1_HUMAN (400-876): 1.96e-147: 445: 22.61
+	Hs
		728155 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		AKT1_HUMAN (400-876): 1.96e-147: 445: 22.61
+	At
		1030913 14332_ARATH (3-243): 8.69e-144: 404: 61.22		CIPKC_ARATH (527-861): 2.17e-115: 362: 28.07
+	At
		840534 14333_ARATH (3-243): 8.04e-143: 401: 61.63		CIPKC_ARATH (527-861): 2.17e-115: 362: 28.07
+	At
		1379653 14337_ARATH (2-243): 2.79e-142: 400: 60.32		CIPKC_ARATH (527-861): 2.17e-115: 362: 28.07
+	Hs
		971420 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		KPCE_HUMAN (74-387): 7.67e-60: 219: 19.51
+	Hs
		690919 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		KPCE_HUMAN (74-387): 7.67e-60: 219: 19.51
+	Hs
		990115 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		KPCE_HUMAN (74-387): 7.67e-60: 219: 19.51
+	Hs
		971778 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		DCLK2_HUMAN (534-809): 1.65e-43: 171: 37.59
+	Mm
		972250 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		DCLK2_MOUSE (534-809): 3.38e-43: 170: 37.59
+	Hs
		690928 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		KPCT_HUMAN (90-401): 1.23e-43: 171: 15.27
+	Hs
		691242 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		DCLK2_HUMAN (534-809): 1.65e-43: 171: 37.59
+	Hs
		971494 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		KCC2D_HUMAN (549-812): 2.36e-41: 160: 36.57
+	Mm
		989991 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		KCC2D_MOUSE (549-812): 2.36e-41: 160: 36.57