HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: RHG23 (Q9P227)
Rho GTPase-activating protein 23 (Rho-type GTPase-activating protein 23)
Gene: ARHGAP23

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	23444366, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1491
+	Hs
		74015 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MYO9A_HUMAN (134-1403): 2.86e-132: 457: 12.17
+	Hs
		73995 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MYO9A_HUMAN (134-1403): 2.86e-132: 457: 12.17
+	Mm
		972298 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		SRGP2_MOUSE (618-1485): 6.77e-96: 336: 15.10
+	Hs
		269535 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		SRGP2_HUMAN (618-1485): 5.42e-93: 328: 14.87
+	Hs
		971624 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		SYDE2_HUMAN (157-1192): 5.4e-91: 324: 14.90
+	Hs
		971710 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		SRGP1_HUMAN (609-1480): 7.86e-92: 324: 14.96
+	Hs
		269513 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		SRGP2_HUMAN (618-1485): 5.42e-93: 328: 14.87
+	Hs
		691105 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		SYDE2_HUMAN (157-1192): 5.4e-91: 324: 14.90
+	Hs
		691183 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		SRGP1_HUMAN (609-1480): 7.86e-92: 324: 14.96
+	Mm
		972260 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		SRGP3_MOUSE (609-1451): 1.29e-87: 312: 15.39
+	Hs
		49956 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		RHG10_HUMAN (627-1257): 1.17e-74: 267: 14.78
+	Hs
		67646 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		RHG32_HUMAN (879-1226): 1.5e-62: 238: 21.16
+	Hs
		67618 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		RHG32_HUMAN (879-1226): 1.5e-62: 238: 21.16
+	Hs
		971615 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		RHG21_HUMAN (31-910): 4.49e-49: 194: 21.76
+	Hs
		691091 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		RHG21_HUMAN (31-910): 4.49e-49: 194: 21.76
+	Hs
		971602 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		Q5JSD8_HUMAN (919-1043): 2.83e-49: 172: 64.00
+	Hs
		691074 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		Q5JSD8_HUMAN (919-1043): 2.83e-49: 172: 64.00
+	Hs
		539991 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		BCR_HUMAN (915-1069): 2.77e-21: 103: 40.00
+	Mm
		989990 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		BCR_MOUSE (903-1069): 5.82e-22: 105: 38.92
+	Hs
		539946 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		BCR_HUMAN (915-1069): 2.77e-21: 103: 40.00