Interactor 1: RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (Nuclear integrity protein 1)
Gene: RPN12

Interactor 2: RPN8 (Q08723)
26S proteasome regulatory subunit RPN8
Gene: RPN8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 11595789, 11805826, 16554755, 16429126, 37968396, 22195964, 22940862, 14759368
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN8_PSD8_EIF3K~MitMem_reg
Common GO terms GO:0000502 - proteasome complex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0034515 - proteasome storage granule
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 274
Sc

1 338
+ Hs
+ Dm
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024