HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: SH2B3 (Q9UQQ2)
SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk)
Gene: SH2B3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 575
+	Hs
		972148 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		SH2B3_HUMAN (1-575): 1.16e-166: 488: 100.00
+	Hs
		990883 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		SH2B3_HUMAN (1-575): 1.16e-166: 488: 100.00
+	Hs
		730366 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		SH2B3_HUMAN (1-575): 1.16e-166: 488: 100.00
+	Hs
		971389 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		GRB2_HUMAN (307-547): 3.38e-46: 163: 12.86
+	Hs
		690888 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		GRB2_HUMAN (307-547): 3.38e-46: 163: 12.86
+	Hs
		987516 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		GRB2_HUMAN (307-547): 3.38e-46: 163: 12.86
+	Hs
		729733 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		GRB2_HUMAN (307-547): 3.38e-46: 163: 12.86
+	Hs
		834166 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		CSK_HUMAN (354-444): 2.07e-32: 131: 29.67
+	Hs
		711295 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		SHC1_HUMAN (350-453): 1.1e-29: 125: 34.62
+	Hs
		834168 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		CSK_HUMAN (354-444): 2.07e-32: 131: 29.67
+	Hs
		711298 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		SHC1_HUMAN (350-453): 1.1e-29: 125: 34.62
+	Hs
		729657 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		CSK_HUMAN (354-444): 2.07e-32: 131: 29.67
+	Hs
		840846 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MATK_HUMAN (343-444): 6.03e-22: 101: 32.35
+	Mm
		148475 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		P85B_MOUSE (329-469): 4.63e-20: 96.3: 18.31
+	Hs
		136358 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		P85B_HUMAN (329-463): 1.65e-18: 91.3: 18.38
+	Gg
		99022 1433E_CHICK (2-243): 1.32e-144: 406: 63.53		KSYK_CHICK (362-492): 2.56e-16: 84.2: 24.11
+	Hs
		136295 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		P85B_HUMAN (329-463): 1.65e-18: 91.3: 18.38
+	Hs
		136364 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		P85B_HUMAN (329-463): 1.65e-18: 91.3: 18.38
+	Hs
		136307 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		P85B_HUMAN (329-463): 1.65e-18: 91.3: 18.38
+	Gg
		99006 1433Z_CHICK (1-245): 7.97e-141: 396: 79.18		KSYK_CHICK (362-492): 2.56e-16: 84.2: 24.11