HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: SH2B3 (Q9UQQ2)
SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk)
Gene: SH2B3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 575
+	Hs
		972148 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		SH2B3_HUMAN (1-575): 1.16e-166: 488: 100.00
+	Hs
		990883 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SH2B3_HUMAN (1-575): 1.16e-166: 488: 100.00
+	Hs
		691550 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		SH2B3_HUMAN (1-575): 1.16e-166: 488: 100.00
+	Hs
		971389 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		GRB2_HUMAN (307-547): 3.38e-46: 163: 12.86
+	Hs
		729733 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		GRB2_HUMAN (307-547): 3.38e-46: 163: 12.86
+	Hs
		987516 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		GRB2_HUMAN (307-547): 3.38e-46: 163: 12.86
+	Hs
		834166 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		CSK_HUMAN (354-444): 2.07e-32: 131: 29.67
+	Hs
		729657 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		CSK_HUMAN (354-444): 2.07e-32: 131: 29.67
+	Hs
		711295 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		SHC1_HUMAN (350-453): 1.1e-29: 125: 34.62
+	Hs
		834168 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		CSK_HUMAN (354-444): 2.07e-32: 131: 29.67
+	Hs
		690888 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		GRB2_HUMAN (307-547): 3.38e-46: 163: 12.86
+	Hs
		711298 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SHC1_HUMAN (350-453): 1.1e-29: 125: 34.62
+	Hs
		840846 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MATK_HUMAN (343-444): 6.03e-22: 101: 32.35
+	Mm
		148475 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		P85B_MOUSE (329-469): 4.63e-20: 96.3: 18.31
+	Hs
		136358 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		P85B_HUMAN (329-463): 1.65e-18: 91.3: 18.38
+	Hs
		136307 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		P85B_HUMAN (329-463): 1.65e-18: 91.3: 18.38
+	Hs
		136364 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		P85B_HUMAN (329-463): 1.65e-18: 91.3: 18.38
+	Gg
		99022 1433E_CHICK (3-243): 4.41e-144: 405: 65.43		KSYK_CHICK (362-492): 2.56e-16: 84.2: 24.11
+	Gg
		99006 1433Z_CHICK (3-244): 7.4e-141: 396: 87.19		KSYK_CHICK (362-492): 2.56e-16: 84.2: 24.11
+	Hs
		136295 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		P85B_HUMAN (329-463): 1.65e-18: 91.3: 18.38