HitPredict

Interactor 1: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Interactor 2: RPN10 (P38886)
26S proteasome regulatory subunit RPN10
Gene: RPN10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.734

Property	Details
Experiments	22940862, 16554755, 16429126, 17499717, 37968396, 14759368
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0008540 - proteasome regulatory particle, base subcomplex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 1 others more... GO:0043248 - proteasome assembly
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 945 Sc			1 268
+	Hs
		874158 PSMD1_HUMAN (3-926): 0: 1116: 39.98		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Hs
		697 A0A087WW66_HUMAN (3-926): 0: 1016: 36.69		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Sp
		251842 RPN2_SCHPO (3-938): 0: 1002: 41.56		RPN10_SCHPO (1-261): 5.8e-112: 323: 45.59
+	Hs
		874086 PSMD2_HUMAN (9-770): 0: 760: 17.31		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Hs
		56615 PSMD2_HUMAN (9-770): 0: 760: 17.31		PIPSL_HUMAN (3-236): 1.17e-110: 340: 44.87
+	Sp
		293408 RPN1_SCHPO (9-770): 0: 621: 18.33		RPN10_SCHPO (1-261): 5.8e-112: 323: 45.59
+	Sc
		753800 RPN1_YEAST (9-573): 1.13e-134: 430: 17.33		RPN10_YEAST (1-268): 3.42e-114: 330: 100.00