HitPredict

Interactor 1: NFIX (Q14938)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Interactor 2: NCOA2 (Q15596)
Nuclear receptor coactivator 2 (NCoA-2) (Class E basic helix-loop-helix protein 75) (bHLHe75) (Transcriptional intermediary factor 2) (hTIF2)
Gene: NCOA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39617063
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 502 Hs			1 1464
+	Hs
		1087755 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		NCOA2_HUMAN (1-1464): 0: 613: 100.00
+	Hs
		1010418 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		SIM1_HUMAN (28-744): 2.55e-105: 355: 16.03
+	Hs
		1133768 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		NCOA3_HUMAN (1-1413): 2.25e-94: 337: 38.39
+	Hs
		1133676 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		ARNT2_HUMAN (1-596): 2.33e-92: 317: 14.88
+	Hs
		1133428 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		NCOA1_HUMAN (1-1460): 1.15e-81: 298: 27.72
+	Hs
		1122900 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		SIM2_HUMAN (28-678): 2.46e-85: 296: 15.76
+	Hs
		777280 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		AHR_HUMAN (4-816): 6.9e-74: 267: 11.77
+	Hs
		693316 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		ARNT_HUMAN (4-662): 1.6e-73: 264: 15.04
+	Hs
		1010417 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		SIM1_HUMAN (28-744): 2.55e-105: 355: 16.03
+	Hs
		473911 NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43		SIM1_HUMAN (28-744): 2.55e-105: 355: 16.03
+	Hs
		1088137 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		NCOA3_HUMAN (1-1413): 2.25e-94: 337: 38.39
+	Hs
		1088034 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		ARNT2_HUMAN (1-596): 2.33e-92: 317: 14.88
+	Hs
		1087761 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		NCOA1_HUMAN (1-1460): 1.15e-81: 298: 27.72
+	Hs
		1087736 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		SIM2_HUMAN (28-678): 2.46e-85: 296: 15.76
+	Hs
		777270 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		AHR_HUMAN (4-816): 6.9e-74: 267: 11.77
+	Hs
		693299 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		ARNT_HUMAN (4-662): 1.6e-73: 264: 15.04
+	Hs
		473826 NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43		AHR_HUMAN (4-816): 6.9e-74: 267: 11.77
+	Hs
		473800 NFIC_HUMAN (3-502): 4.99e-114: 348: 53.43		ARNT_HUMAN (4-662): 1.6e-73: 264: 15.04
+	Hs
		1133540 NFIX_HUMAN (1-502): 5.28e-159: 462: 100.00		KMT2C_HUMAN (670-1422): 5.03e-11: 70.1: 13.05
+	Hs
		1087875 NFIA_HUMAN (1-502): 1.45e-118: 359: 66.47		KMT2C_HUMAN (670-1422): 5.03e-11: 70.1: 13.05