HitPredict

Interactor 1: CHD1 (P32657)
Chromo domain-containing protein 1 (EC 3.6.4.-) (ATP-dependent helicase CHD1)
Gene: CHD1

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0031490 - chromatin DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1468 Sc			1 134
+	Sc
		392087 CHD1_YEAST (1-1468): 0: 1114: 100.00		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392360 CHD1_YEAST (1-1468): 0: 1114: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Sp
		144532 HRP3_SCHPO (7-1463): 0: 914: 46.24		H2A1_SCHPO (10-133): 1.77e-51: 161: 56.80
+	Sp
		144533 HRP3_SCHPO (7-1463): 0: 914: 46.24		H2A2_SCHPO (10-131): 1.29e-51: 161: 58.54
+	Hs
		470170 CHD8_HUMAN (2-1377): 0: 934: 26.15		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		391915 CHD8_HUMAN (2-1377): 0: 934: 26.15		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391728 CHD9_HUMAN (20-1378): 0: 921: 26.06		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		151474 CHD2_HUMAN (5-1468): 0: 876: 31.11		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		229433 SMCA5_HUMAN (245-1274): 0: 777: 26.33		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		469951 SMCA1_HUMAN (253-1259): 0: 778: 27.19		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		229286 SMCA5_HUMAN (245-1274): 0: 777: 26.33		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		469971 SMCA4_HUMAN (3-1106): 0: 755: 23.19		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		229279 SMCA5_HUMAN (245-1274): 0: 777: 26.33		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Mm
		470232 SMCA4_MOUSE (3-1106): 0: 748: 23.25		H2AZ_MOUSE (10-134): 6.73e-41: 134: 67.72
+	Sc
		996427 ISW2_YEAST (364-933): 1.41e-126: 424: 42.98		H2AZ_YEAST (1-134): 2.81e-53: 165: 100.00
+	Sc
		392595 ISW2_YEAST (364-933): 1.41e-126: 424: 42.98		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		1018640 CHD3_HUMAN (959-1364): 1.33e-13: 78.5: 9.57		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		470021 CHD4_HUMAN (959-1353): 6.6e-11: 69.7: 12.19		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		391675 CHD3_HUMAN (959-1364): 1.33e-13: 78.5: 9.57		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391704 CHD4_HUMAN (959-1353): 6.6e-11: 69.7: 12.19		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83