HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: DJC10 (Q8IXB1)
DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr)
Gene: DNAJC10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0016020 - membrane GO:0034975 - protein folding in endoplasmic reticulum GO:0036503 - ERAD pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 592 Hs			1 793
+	Hs
		697944 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		DJC10_HUMAN (1-793): 0: 606: 100.00
+	Hs
		699273 CALX_HUMAN (1-592): 0: 786: 100.00		DJC16_HUMAN (18-249): 1.36e-63: 229: 30.83
+	Hs
		566561 CALX_HUMAN (1-592): 0: 786: 100.00		PDIA4_HUMAN (138-674): 4.39e-32: 134: 13.47
+	Hs
		698415 CALX_HUMAN (1-592): 0: 786: 100.00		PDIA3_HUMAN (235-674): 1.4e-26: 116: 13.53
+	Hs
		699222 CALX_HUMAN (1-592): 0: 786: 100.00		DJB11_HUMAN (19-108): 1.04e-22: 102: 47.78
+	Hs
		699221 CALX_HUMAN (1-592): 0: 786: 100.00		DNJB9_HUMAN (19-128): 4.04e-16: 80.1: 40.00
+	Rn
		547735 CALX_RAT (1-592): 0: 740: 91.06		PDIA3_RAT (236-674): 1.24e-25: 113: 12.92
+	Hs
		452173 CALX_HUMAN (1-592): 0: 786: 100.00		PDIA1_HUMAN (85-231): 6.8e-09: 61.2: 17.88
+	Dm
		1465253 Q9VAL7_DROME (33-592): 0: 633: 49.74		PDIA6_DROME (123-353): 2.71e-36: 144: 21.40
+	Dm
		929535 Q9VAL7_DROME (33-592): 0: 633: 49.74		PDI_DROME (232-669): 8.73e-20: 95.5: 13.22
+	Hs
		697886 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		PDIA6_HUMAN (137-453): 5.89e-39: 152: 16.35
+	Hs
		566560 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		PDIA4_HUMAN (138-674): 4.39e-32: 134: 13.47
+	Hs
		697864 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		PDIA2_HUMAN (463-791): 2.58e-32: 134: 17.46
+	Hs
		566803 CALR3_HUMAN (64-470): 4.24e-135: 400: 26.59		PDIA4_HUMAN (138-674): 4.39e-32: 134: 13.47
+	Hs
		697777 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		PDIA3_HUMAN (235-674): 1.4e-26: 116: 13.53
+	Hs
		698060 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		DJB11_HUMAN (19-108): 1.04e-22: 102: 47.78
+	Hs
		717574 CALR3_HUMAN (64-470): 4.24e-135: 400: 26.59		PDIA3_HUMAN (235-674): 1.4e-26: 116: 13.53
+	Hs
		698059 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		DNJB9_HUMAN (19-128): 4.04e-16: 80.1: 40.00
+	At
		146277 CALR1_ARATH (64-467): 6.43e-135: 401: 33.09		PDI21_ARATH (240-451): 1.67e-15: 80.9: 15.95
+	Hs
		452369 CALR3_HUMAN (64-470): 4.24e-135: 400: 26.59		PDIA1_HUMAN (85-231): 6.8e-09: 61.2: 17.88