HitPredict

Interactor 1: DRS1 (P32892)
ATP-dependent RNA helicase DRS1 (EC 3.6.4.13) (Deficiency of ribosomal subunits protein 1)
Gene: DRS1

Interactor 2: SSF1 (P38789)
Ribosome biogenesis protein SSF1
Gene: SSF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	11805826, 26823502, 37968396, 11864607, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 752 Sc			1 453
+	Sc
		699748 DRS1_YEAST (1-752): 7.49e-162: 488: 100.00		SSF2_YEAST (1-453): 0: 538: 94.04
+	Sc
		415968 DED1_YEAST (166-616): 3.67e-117: 367: 24.63		SSF1_YEAST (1-453): 0: 544: 100.00
+	Hs
		1292660 DDX27_HUMAN (33-735): 1.49e-129: 405: 33.66		SSF1_HUMAN (2-453): 3.49e-142: 417: 32.33
+	Sc
		754899 HAS1_YEAST (195-583): 2.19e-72: 246: 37.69		SSF1_YEAST (1-453): 0: 544: 100.00
+	Sc
		976889 HAS1_YEAST (195-583): 2.19e-72: 246: 37.69		SSF2_YEAST (1-453): 0: 538: 94.04
+	Hs
		1254818 DDX54_HUMAN (226-584): 3.38e-64: 231: 40.67		SSF1_HUMAN (2-453): 3.49e-142: 417: 32.33
+	Hs
		1343143 DDX18_HUMAN (167-578): 1.17e-57: 209: 34.69		SSF1_HUMAN (2-453): 3.49e-142: 417: 32.33