HitPredict

Interactor 1: PSB5 (P28074)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X) (Proteasome subunit beta-5) (beta-5)
Gene: PSMB5

Interactor 2: FBX7 (Q9Y3I1)
F-box only protein 7
Gene: FBXO7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27503909
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 522
+	Hs
		700490 PSB8_HUMAN (1-261): 3.69e-88: 264: 57.46		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		700766 PSA5_HUMAN (28-258): 9.79e-86: 257: 15.64		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		1404134 PSB7_HUMAN (39-251): 7.53e-82: 248: 25.82		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		681246 PSA2_HUMAN (30-259): 3.22e-79: 240: 18.64		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		681748 PSA4_HUMAN (32-255): 4.73e-79: 240: 18.22		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		701096 PSB6_HUMAN (43-245): 6.74e-77: 234: 31.37		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		700550 PSB9_HUMAN (55-242): 2.59e-18: 82.8: 30.16		FBX7_HUMAN (1-522): 0: 1102: 100.00