HitPredict

Interactor 1: NOS2 (P29477)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC-NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2

Interactor 2: RAC2 (Q05144)
Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (Protein EN-7) (p21-Rac2)
Gene: RAC2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.529

Property	Details
Experiments	11457725
Identification Methods	two hybrid, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1144 Mm			1 192
+	Mm
		713193 NOS2_MOUSE (1-1144): 0: 1807: 100.00		RAC1_MOUSE (1-192): 9.6e-85: 250: 91.67
+	Hs
		766176 NOS2_HUMAN (1-1144): 0: 1775: 80.78		RAC1_HUMAN (1-192): 9.6e-85: 250: 91.67
+	Hs
		580898 NOS2_HUMAN (1-1144): 0: 1775: 80.78		RAC2_HUMAN (1-192): 4.17e-82: 243: 98.96
+	Hs
		596637 NCPR_HUMAN (496-1122): 0: 737: 29.06		RAC1_HUMAN (1-192): 9.6e-85: 250: 91.67
+	Hs
		580862 NCPR_HUMAN (496-1122): 0: 737: 29.06		RAC2_HUMAN (1-192): 4.17e-82: 243: 98.96
+	Hs
		596632 NCPR_HUMAN (496-1122): 0: 737: 29.06		RAC3_HUMAN (1-191): 5.53e-79: 235: 88.48
+	Hs
		596639 NCPR_HUMAN (496-1122): 0: 737: 29.06		RHOG_HUMAN (1-192): 1.16e-78: 234: 69.79
+	Hs
		596633 NCPR_HUMAN (496-1122): 0: 737: 29.06		CDC42_HUMAN (1-192): 2.33e-77: 231: 69.27
+	Hs
		596635 NCPR_HUMAN (496-1122): 0: 737: 29.06		RHOA_HUMAN (5-192): 2.28e-75: 226: 54.26
+	Hs
		466095 NCPR_HUMAN (496-1122): 0: 737: 29.06		RHOC_HUMAN (5-192): 3.44e-72: 218: 54.79