HitPredict

Interactor 1: RYK (P34925)
Tyrosine-protein kinase RYK (EC 2.7.10.1)
Gene: RYK

Interactor 2: PCDGH (Q9Y5G0)
Protocadherin gamma-B5 (PCDH-gamma-B5)
Gene: PCDHGB5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.618

Property	Details
Experiments	33961781, 35384245
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 607 Hs			1 923
+	Hs
		713899 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDG5_HUMAN (2-908): 0: 1128: 53.27
+	Hs
		523229 SRC_HUMAN (315-602): 2.06e-108: 338: 30.80		PCDG5_HUMAN (2-908): 0: 1128: 53.27
+	Hs
		713894 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDB2_HUMAN (1-773): 0: 948: 44.56
+	Hs
		508294 FGFR1_HUMAN (137-599): 4.53e-145: 441: 27.29		PCDB7_HUMAN (12-764): 0: 594: 45.96
+	Hs
		713884 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCD10_HUMAN (16-723): 0: 574: 42.88
+	Hs
		385795 NTRK1_HUMAN (122-607): 2.22e-129: 400: 25.65		PCDB3_HUMAN (1-764): 0: 604: 45.12
+	Hs
		433517 YES_HUMAN (315-602): 3.09e-108: 337: 31.14		PCDB3_HUMAN (1-764): 0: 604: 45.12
+	Hs
		523182 SRC_HUMAN (315-602): 2.06e-108: 338: 30.80		PCD10_HUMAN (16-723): 0: 574: 42.88
+	Hs
		674578 UFO_HUMAN (315-603): 3.55e-55: 203: 37.63		PCDB3_HUMAN (1-764): 0: 604: 45.12
+	Hs
		231356 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDGC_HUMAN (2-440): 6.51e-95: 321: 26.25
+	Hs
		508295 FGFR1_HUMAN (137-599): 4.53e-145: 441: 27.29		PCDA8_HUMAN (5-438): 3.76e-93: 317: 26.84
+	Hs
		713897 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDG7_HUMAN (2-440): 8.05e-94: 318: 26.25
+	Hs
		713898 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDG6_HUMAN (2-440): 1.19e-92: 315: 27.33
+	Hs
		713895 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDGL_HUMAN (5-439): 8.23e-87: 299: 25.44
+	Hs
		713900 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDGB_HUMAN (1-343): 6.71e-57: 214: 23.97
+	Hs
		713888 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDGK_HUMAN (5-233): 3.34e-28: 124: 20.75
+	Mm
		555033 MET_MOUSE (330-593): 4.01e-59: 216: 39.47		PCDAA_MOUSE (5-472): 2.98e-91: 312: 25.86
+	Hs
		385714 NTRK1_HUMAN (122-607): 2.22e-129: 400: 25.65		PCDGK_HUMAN (5-233): 3.34e-28: 124: 20.75
+	Hs
		523204 SRC_HUMAN (315-602): 2.06e-108: 338: 30.80		PCDGK_HUMAN (5-233): 3.34e-28: 124: 20.75
+	Hs
		433505 YES_HUMAN (315-602): 3.09e-108: 337: 31.14		PCDGK_HUMAN (5-233): 3.34e-28: 124: 20.75