HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21951318
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Hs			1 530
+	Hs
		369085 HSP74_HUMAN (1-840): 0: 993: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1267724 HS105_HUMAN (1-840): 0: 938: 62.95		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		320786 HS74L_HUMAN (1-840): 0: 959: 63.21		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370116 HS105_HUMAN (1-840): 0: 938: 62.95		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377137 HSP74_HUMAN (1-840): 0: 993: 100.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Rn
		291976 HSP74_RAT (1-840): 0: 979: 95.83		GCR_RAT (3-495): 5.89e-100: 321: 23.03
+	Hs
		611477 HS105_HUMAN (1-840): 0: 938: 62.95		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		414450 HSP74_HUMAN (1-840): 0: 993: 100.00		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		487177 HSP74_HUMAN (1-840): 0: 993: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		504498 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		714036 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368878 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369084 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		320162 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		ERR2_HUMAN (69-499): 5.86e-109: 333: 31.57
+	Hs
		377052 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487886 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		504003 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		NR1H3_HUMAN (65-499): 1.77e-104: 322: 20.97
+	Hs
		503444 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		414425 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		487079 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59