HitPredict

Interactor 1: PHB1 (P35232)
Prohibitin 1
Gene: PHB1

Interactor 2: TPTE (P56180)
Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Cancer/testis antigen 44) (CT44) (Transmembrane phosphatase with tensin homology) (Tumor antigen BJ-HCC-5)
Gene: TPTE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	27432908, 28330616
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0008285 - negative regulation of cell population proliferation GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 551
+	Hs
		879840 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		TPTE_HUMAN (1-551): 0: 759: 100.00
+	Mm
		139364 PHB1_MOUSE (1-272): 5.99e-92: 274: 99.63		PTEN_MOUSE (215-550): 1.45e-106: 327: 32.44
+	Hs
		718669 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		PTEN_HUMAN (215-550): 1.26e-106: 327: 32.44
+	Mm
		139285 PHB2_MOUSE (6-267): 1.38e-85: 259: 50.57		PTEN_MOUSE (215-550): 1.45e-106: 327: 32.44
+	Hs
		890817 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		PTEN_HUMAN (215-550): 1.26e-106: 327: 32.44